Recombinant Human SIGLEC6 Protein (27-347), C-Fc-Avi tagged

• Cat.No.: SIGLEC6-13H
• Product Overview: Human secreted Sialic Acid Binding Ig Like Lectin 6 (Siglec6)-Fc fusion protein, also known as CD33 Antigen-Like 1 (CD33L1) and Obesity-Binding Protein 1 (OBBP1), GenBank Accession No. NM_001245, a.a. 27-347, fused at the C-terminus of the Fc portion of human IgG1, with C-terminal Avi-tag, expressed in a HEK293 cell expression system and enzymatically biotinylated using Avi-tag™ technology. Biotinylation is confirmed to be ≥90 %. This protein runs at a higher molecular weight due to glycosylation.

Specification

• Species: Human
• Source: HEK293
• Tag: Avi&Fc
• Protein Length: 27-347
• Description: This gene encodes a member of the SIGLEC (sialic acid binding immunoglobulin-like lectin) family of proteins. The encoded transmembrane receptor binds sialyl-TN glycans and leptin. Placental expression of the encoded protein is upregulated in preeclampsia.
• Form: Aqueous buffer solution
• Molecular Mass: 64 kDa
• Purity: ≥90 %
• Storage: At least 6 months at –80 centigrade.
• Storage Buffer: 8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20 % glycerol.
• Shipping: At -80 centigrade
• Warning: Avoid freeze/thaw cycles.

Gene Information

• Gene Name: SIGLEC6 sialic acid binding Ig like lectin 6 [ Homo sapiens (human) ]
• Official Symbol: SIGLEC6
• Synonyms: SIGLEC6; sialic acid binding Ig like lectin 6; CD327; CD33L; OBBP1; CD33L1; CD33L2; CDW327; sialic acid-binding Ig-like lectin 6; CD33 antigen-like 1; obesity-binding protein 1
• Gene ID: 946
• mRNA Refseq: NM_001245
• Protein Refseq: NP_001236
• MIM: 604405
• UniProt ID: O43699