Recombinant Human SIGLEC6 Protein, Fc-His-tagged

• Cat.No.: SIGLEC6-55H
• Product Overview: Recombinant human SIGLEC6 protein, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: Insect Cells
• Tag: Fc&His
• Description: SIGLEC6, also known as sialic acid-binding Ig-like lectin 6 isoform 1, is one of immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. It mediates sialic-acid dependent binding to cells and binds to alpha-2, 6-linked sialic acid. This protein localizes in various compartments such as membrane fraction, extracellular region and so on.
• Form: Liquid
• Molecular Mass: 70-100KDa (SDS-PAGE under reducing conditions.)
• AA sequence: ADLQERRFQL EGPESLTVQE GLCVLVPCRL PTTLPASYYG YGYWFLEGAD VPVATNDPDE EVQEETRGRF HLLWDPRRKN CSLSIRDARR RDNAAYFFRL KSKWMKYGYT SSKLSVRVMA LTHRPNISIP GTLESGHPSN LTCSVPWVCE QGTPPIFSWM SAAPTSLGPR TTQSSVLTIT PRPQDHSTNL TCQVTFPGAG VTMERTIQLN VSYAPQKVAI SIFQGNSAAF KILQNTSSLP VLEGQALRLL CDADGNPPAH LSWFQGFPAL NATPISNTGV LELPQVGSAE EGDFTCRAQH PLGSLQISLS LFVHWKPEGR AGGVLEPKSC DKTHTCPPCP APELLGGPSV FLFPPKPKDT
  LMISRTPEVT CVVVDVSHED PEVKFNWYVD GVEVHNAKTK PREEQYNSTY RVVSVLTVLH QDWLNGKEYK CKVSNKALPA PIEKTISKAK GQPREPQVYT LPPSRDELTK NQVSLTCLVK GFYPSDIAVE WESNGQPENN YKTTPPVLDS DGSFFLYSKL TVDKSRWQQG NVFSCSVMHE ALHNHYTQKS LSLSPGKHHH HHH
• Endotoxin: < 1.0 EU per 1μg of protein (determined by LAL method)
• Purity: > 90% by SDS - PAGE
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5mg/ml
• Storage buffer: In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.

Gene Information

• Gene Name: SIGLEC6 sialic acid binding Ig-like lectin 6 [ Homo sapiens ]
• Official Symbol: SIGLEC6
• Synonyms: SIGLEC6; sialic acid binding Ig-like lectin 6; CD33L, CD33L1; sialic acid-binding Ig-like lectin 6; CD327; OB BP1; SIGLEC 6; CD33 antigen-like 1; obesity-binding protein 1; CD33L; OBBP1; CD33L1; CD33L2; CDW327
• Gene ID: 946
• mRNA Refseq: NM_001177547
• Protein Refseq: NP_001171018
• MIM: 604405
• UniProt ID: O43699