"PTPN9" Related Products

Expand
Expand
Expand

Recombinant Human Protein Tyrosine Phosphatase, Non-Receptor Type 9

Cat. No.: PTPN9-1910H
Product Overview: Recombinant humanPTPN9 is expressed in E. coli; it contains the catalytic domain of PTPN9(residues 285-593) and has a molecular weight of 34.3 kDa.
Description: PTPN9 (proteintyrosine phosphatase from megakaryocyte-2) was originally cloned from humanMEG-01 megakaryocyte and umbilical vein endothelial cell cDNA. The catalyticdomain is located at the carboxy-terminus of the full-length protein and ithas 30-40% sequence identity to other known protein tyrosine phosphatases.The full-length enzyme has been reported to bind phospholipid with highaffinity and that this binding is important for MEG2 activity on secretoryvesicles.
Source: E. coli
Species: Human
Form: 25 mM Tris-HCl (pH8.0), 75 mM NaCl, 0.05% Tween-20, 2 mM EDTA, 1 mM DTT and 50% glycerol.Liquid at -20°C.
Purity: Greater than 95% asdetermined by Coomassie-stained SDS-PAGE gel.
Specific Activity: 3.5 U/μg. One unitwill hydrolyze 1 nmol of p-nitrophenyl phosphate per minute at pH 7.4 and30°C. Assay buffer: 50 mM HEPES (pH 7.4), 2 mM EDTA, 3 mM DTT, 100 mM NaCland 50 mM pNPP.
Applications: Removal ofphosphates from target substrates. Useful for the study of enzyme kinetics,regulation and for inhibitors screening.
Storage: 6 months at -20°C.
Gene Name: PTPN9 protein tyrosinephosphatase, non-receptor type 9 [ Homo sapiens ]
Official Symbol: PTPN9
Synonyms: PTPN9; proteintyrosine phosphatase, non-receptor type 9; MEG2; PTPMEG2; tyrosine-proteinphosphatase non-receptor type 9; PTPase MEG2; PTPase-MEG2; OTTHUMP00000183522;protein-tyrosine phosphatase MEG2
Gene ID: 5780
mRNA Refseq: NM_002833
Protein Refseq: NP_002824
MIM: 600768
UniProt ID: P43378
Chromosome Location: 15q23
Function: hydrolase activity;non-membrane spanning protein tyrosine phosphatase activity; protein binding;protein tyrosine phosphatase activity

Online Inquiry

Note: There will be extra charge for optional service!
Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information


Price does not include shipping and packaging costs.Request quote for final price.

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.