Native Pig Amylase, Alpha 2B (pancreatic)
Cat.No. : | AMY2-5364P |
Product Overview : | Native pig AMY2 was expressed in Pig pancreas. |
- Specification
- Gene Information
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Description : | AMY2 are secreted proteins thathydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides,and thus catalyze the first step in digestion of dietary starch and glycogen.The human genome has a cluster of several amylase genes that are expressed athigh levels in either salivary gland or pancreas. This gene encodes anamylase isoenzyme produced by the pancreas. |
Source : | Pig pancreas |
Species : | Pig |
Form : | Lyophilized from 150mM NaCl +3 mM CaCl. |
Molecular Mass : | 54 kDa |
Storage : | Product is stablefor 2 years when stored at -20°C. |
Concentration : | Typically >0.5mg/ml |
Gene Name : | AMY2 amylase, alpha 2B (pancreatic) [ Sus scrofa ] |
Official Symbol : | AMY2 |
Synonyms : | AMY2B; pancreatic alpha-amylase; PA; alpha-amylase; 1,4-alpha-D-glucan glucanohydrolase |
mRNA Refseq : | NM_214195 |
Protein Refseq : | NP_999360 |
UniProt ID : | P00690 |
Chromosome Location : | 4; 4 |
Pathway : | Carbohydrate digestion and absorption, organism-specific biosystem; Digestion of dietary carbohydrate, organism-specific biosystem; Metabolism of carbohydrates, organism-specific biosystem |
Function : | alpha-amylase activity; calcium ion binding; chloride ion binding |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionThe AMY2 protein works by breaking the bonds that hold together the glucose units in starch molecules. It cleaves these bonds, resulting in the production of smaller carbohydrate molecules, such as maltose and maltotriose, which can be further broken down into glucose for absorption.
Yes, variations in the AMY2 gene can affect carbohydrate digestion. Individuals with more copies of the AMY2 gene may have an advantage in digesting starch-rich diets more efficiently, while those with fewer copies may have reduced carbohydrate-digesting capacity.
Having more copies of the AMY2 gene may provide certain benefits in carbohydrate digestion. It can lead to higher levels of AMY2 protein production, which may enhance the breakdown and absorption of complex carbohydrates. This can potentially result in better energy utilization and nutrient absorption from carbohydrate-rich foods.
The production and activity of the AMY2 protein can be influenced by several dietary and environmental factors. Diets low in carbohydrates may result in lower levels of AMY2 protein production. On the other hand, diets high in carbohydrates can lead to increased production of AMY2 protein. In addition, factors like stress, hormones, and certain medications can also impact the production and functionality of the AMY2 protein.
The AMY2 protein itself is not directly involved in any health conditions or disorders. However, variations in the AMY2 gene and differences in AMY2 protein levels have been associated with differences in carbohydrate metabolism, which can have implications for conditions such as obesity, diabetes, and metabolic syndrome.
Yes, there are genetic variations in the AMY2 gene. Some individuals may have more copies of the AMY2 gene, leading to higher levels of AMY2 protein production and potentially better carbohydrate digestion. This genetic variation is believed to have evolved in populations that historically consumed diets rich in starch.
Yes, the AMY2 gene can be tested for variations. Genetic tests can identify the number of copies of the AMY2 gene an individual has and provide insights into their potential carbohydrate-digesting capacity. However, it's important to note that the impact of these genetic variations on individual health outcomes is complex and may be influenced by various other factors.
Yes, variations in the AMY2 gene have been studied in relation to obesity and diabetes. Some research suggests that individuals with a higher number of AMY2 gene copies may have a lower risk of these conditions, as their increased carbohydrate-digesting capacity may contribute to better overall metabolic health. However, it's important to note that genetic factors are just one piece of the puzzle, and lifestyle factors such as diet and physical activity also play significant roles in obesity and diabetes risk.
Having fewer copies of the AMY2 gene can potentially lead to reduced carbohydrate-digesting capacity. This may result in difficulties in breaking down complex carbohydrates efficiently and extracting energy from them. In the context of modern diets that are often high in carbohydrates, individuals with fewer copies of the AMY2 gene may be at a disadvantage in terms of carbohydrate metabolism and energy utilization.
There are currently no supplements or medications available specifically to enhance the activity or production of the AMY2 protein. The body naturally produces the AMY2 protein based on its needs, primarily stimulated by the presence of carbohydrates in the diet. However, adopting a balanced diet that includes adequate carbohydrate intake may support the natural production and activity of the AMY2 protein.
Customer Reviews (4)
Write a reviewThis flexibility allows researchers to focus on specific aspects of AMY2 protein functionality, regulation, or disease associations, enhancing the relevance and applicability of their work.
Such manufacturer support fosters a conducive environment for successful and impactful research outcomes.
By considering these advantages and the supportive role of manufacturers, researchers studying AMY2 protein can benefit from high-quality products, technical assistance, customization options, product validation, and potential collaborations.
This information ensures that researchers have a clear understanding of the product's performance attributes, and enables them to select the most suitable protein preparation for their experiments.
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