"TMPRSS15" Related Products


Recombinant Human Transmembrane Protease, Serine 15

Cat. No.: TMPRSS15-1279H
Product Overview: Enteropeptidase Human is a specific protease that cleaves after the sequence Asp-Asp-Aps-Aps-Lys. The light chain of enteropeptidase has full enzymatic activity. No other protease activity was detected. Human enteropeptidase binds specifically to STI-agarose. The affinity puirifed Human Enterokinase contains amino acids 785-1019.
Description: Enteropeptidase or enterokinase is an enzymeinvolved in human digestion. It is produced by cells in the duodenum wall, and is secreted from duodenum"s glands, the crypts of Lieberk?hn, whenever ingested food enters the duodenum from the stomach. Enteropeptidase has the critical job of turning trypsinogen(a zymogen) to trypsin, indirectly activating a number of pancreaticdigestive enzymes. Enteropeptidase is a serine proteaseenzyme(EC3.4.21.9). Enteropeptidase is a part of the Chymotrypsin-clan of serine proteases, and is structurally similar to these proteins.
Source: Human
Host: Escherichia Coli.
Form: 50mM Tris-HCl, pH 8.0, 0.5M NaCl, 1mM CaCl2 and 50% glycerol.
Purity: Greater than 98.0% as determined by SDS-PAGE.
Physical Appearance: Liquid solution.
Storage: One year when stored at ?C20°C, three weeks at room temperature.
Gene Name: TMPRSS15 transmembrane protease, serine 15 [ Homo sapiens ]
Official Symbol: TMPRSS15
Synonyms: TMPRSS15; transmembrane protease, serine 15; ENTK; PRSS7; MGC133046; enteropeptidase; enterokinase; serine protease 7; OTTHUMP00000083248; protease, serine, 7 (enterokinase); Enteropeptidase; Enterokinase; Serine protease 7; Transmembrane protease serine 15; EC; EC 3.4.21
Gene ID: 5651
mRNA Refseq: NM_002772
Protein Refseq: NP_002763
MIM: 606635
UniProt ID: P98073
Chromosome Location: 21q21; 21q21.1
Function: peptidase activity; scavenger receptor activity; serine-type endopeptidase activity

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