Recombinant Human CLCN2, His-tagged

• Cat.No.: CLCN2-11279H
• Product Overview: Recombinant Human CLCN2 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: C-term-350a.a.
• Description: This gene encodes a voltage-gated chloride channel. The encoded protein is a transmembrane protein that maintains chloride ion homeostasis in various cells. Defects in this gene may be a cause of certain epilepsies. Four transcript variants encoding different isoforms have been found for this gene.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: CLCN2 chloride channel, voltage-sensitive 2 [ Homo sapiens ]
• Official Symbol: CLCN2
• Synonyms: CLCN2; chloride channel, voltage-sensitive 2; chloride channel 2; chloride channel protein 2; ClC 2; CLC2; EJM6; ECA2; ECA3; EGI3; EGMA; EJM8; CIC-2; EGI11; clC-2
• Gene ID: 1181
• mRNA Refseq: NM_001171087
• Protein Refseq: NP_001164558
• MIM: 600570
• UniProt ID: P51788
• Chromosome Location: 3q26-qter
• Pathway: Mineral absorption, organism-specific biosystem; Mineral absorption, conserved biosystem
• Function: voltage-gated chloride channel activity; voltage-gated ion channel activity