Recombinant Human CDH2, His-Fc tagged

• Cat.No.: CDH2-315H
• Product Overview: Recombinant Human CDH2 (NP_001783.2) (Met1-Ala724), fused with the C-terminal polyhistidine-tagged Fc region of human IgG1, was produced in Human Cells.

Specification

• Source: Human Cells
• Species: Human
• Tag: His-Fc
• Predicted N Terminal: Asp 160
• Form: Lyophilized from sterile PBS, pH 7.4.Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization.
• Molecular Mass: The secreted recombinant human CDH2 is a disulfide-linked homodimeric protein. The reduced monomer comprises 813 amino acids and has a predicted molecular mass of 89.9 kDa. As a result of glycosylation, it migrates as an approximately 114 and 119 kDa band
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >70 % as determined by SDS-PAGE
• Stability: Samples are stable for up to twelve months from date of receipt at -70oC.
• Storage: Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4℃ before opening to recover the entire contents.
• Publication:
  A mechanically active heterotypic E-cadherin/N-cadherin adhesion enables fibroblasts to drive cancer cell invasion (2017)

Gene Information

• Gene Name: CDH2 cadherin 2, type 1, N-cadherin (neuronal) [ Homo sapiens ]
• Official Symbol: CDH2
• Gene ID: 1000
• mRNA Refseq: NM_001792
• Protein Refseq: NP_001783
• MIM: 114020
• UniProt ID: P19022
• Chromosome Location: 18q12.1