Recombinant Human YSK4 (MAP3K19), GST-tagged

• Cat.No.: YSK4-57H
• Product Overview: Recombinant human YSK4 (MAP3K19) (941-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Description: YSK4 (MAP3K19, RCK) belongs to STE Ser/Thr protein kinase family and STE20 subfamily. The YSK4 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, and rat. The important paralog is MAP3K1 gene. The RCK ligand-binding domains form an octameric gating ring in the large-conductance Ca2+-activated K+ channels. The YSK4 kinase function has not been made clearly yet.
• Source: Sf9 insect cells using baculovirus
• Species: Human
• Tag: GST
• Form: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Molecular Mass: ~83 kDa
• Applications: Kinase Assay, Western Blot
• Storage: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: YSK4 YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: YSK4
• Synonyms: YSK4; YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae); yeast Sps1/Ste20 related kinase 4 (S. cerevisiae) , Yeast Sps1/Ste20 related kinase 4 (S. cerevisiae); SPS1/STE20-related protein kinase YSK4; FLJ23074; regulated in COPD kinase; regulated in COPD, protein kinase; yeast Sps1/Ste20-related kinase 4; RCK
• Gene ID: 80122
• mRNA Refseq: NM_001018046
• Protein Refseq: NP_001018056
• UniProt ID: Q56UN5
• Chromosome Location: 2q21.3
• Function: ATP binding; nucleotide binding; protein serine/threonine kinase activity