Active Recombinant Human LGALS9 protein
Cat.No. : | LGALS9-443H |
Product Overview : | Recombinant Human LGALS9(Ala2-Thr323) was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Source : | E. coli |
Species : | Human |
Predicted N Terminal : | Ala2 |
Form : | Lyophilized from a 0.2 μm filtered solution in MOPS, NaCl, EDTA, DTT and Trehalose. |
Bio-activity : | Measured by its ability to induce apoptosis of Jurkat human acute T cell leukemia cells. Lu, L.H. et al. (2007) J. Biochem. 141:157. The ED50 for this effect is typically 1-5 μg/mL. Measured by its ability to agglutinate human red blood cells. Hadari, Y.R. et al. (2000) J. Cell Sci. 113:2385. The ED50 for this effect is typically 2.5-12.5 µg/mL. |
Molecular Mass : | Predicted Molecular Mass: 35.8 kDa;SDS-PAGE: 34 kDa, reducing conditions. |
Endotoxin : | <1.0 EU per 1 μg of the protein by the LAL method. |
Purity : | >95%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
Storage : | Avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 centigrade as supplied.1 month, 2 to 8 centigrade under sterile conditions after reconstitution.3 months, -20 to -70 centigrade under sterile conditions after reconstitution. |
Reconstitution : | Reconstitute at 100 μg/mL in water. |
Gene Name : | LGALS9 lectin, galactoside-binding, soluble, 9 [ Homo sapiens ] |
Official Symbol : | LGALS9 |
Synonyms : | LGALS9; lectin, galactoside-binding, soluble, 9; galectin-9; galectin 9; LGALS9A; gal-9; ecalectin; tumor antigen HOM-HD-21; urate transporter/channel protein; HUAT; MGC117375; MGC125973; MGC125974; |
Gene ID : | 3965 |
mRNA Refseq : | NM_002308 |
Protein Refseq : | NP_002299 |
MIM : | 601879 |
UniProt ID : | O00182 |
Chromosome Location : | 17q11.2 |
Pathway : | 1. Germinal center kinase-like kinase (GLK/MAP4K3) expression is increased in adult-onset Still's disease and may act as an activity marker. Chen DY, et al. BMC Med, 2012 Aug 6. 2. MAP4K3 enhances the expression of the BH3-only protein BID. Lam D, et al. Cell Cycle, 2009 Oct 15. 3. Activation of the c-Jun N-terminal kinase pathway by a novel protein kinase related to human germinal center kinase. Diener K, et al. Proc Natl Acad Sci U S A, 1997 Sep 2. |
Function : | galactose binding; signal transducer activity; sugar binding; sugar binding; |
Products Types
◆ Recombinant Protein | ||
LGALS9-5058M | Recombinant Mouse LGALS9 Protein, His (Fc)-Avi-tagged | +Inquiry |
LGALS9-660H | Recombinant Human LGALS9 Protein | +Inquiry |
LGALS9-3048R | Recombinant Rat LGALS9 Protein, His (Fc)-Avi-tagged | +Inquiry |
LGALS9-2391D | Recombinant Dog LGALS9 Protein, His-tagged | +Inquiry |
Lgals9-435M | Recombinant Mouse Lgals9 Protein(Met1-Thr322), GST-tagged | +Inquiry |
◆ Lysates | ||
LGALS9-4761HCL | Recombinant Human LGALS9 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionYes, there are clinical trials investigating the use of LGALS9-based therapies in cancer treatment, with a focus on immunotherapy approaches.
There is emerging research on the potential use of LGALS9 in modulating immune responses to infectious diseases, particularly in the context of viral infections.
Challenges include optimizing the delivery and dosing of LGALS9-based therapies and addressing potential adverse effects on immune homeostasis.
LGALS9 is being investigated for its potential to induce immune tolerance and mitigate transplant rejection in preclinical studies.
LGALS9 has been found to promote the activation and proliferation of cytotoxic T lymphocytes, which are key players in the immune response against cancer cells.
Customer Reviews (3)
Write a reviewIt has demonstrated outstanding performance in ELISA, providing reliable and precise results.
It has been invaluable in protein electron microscopy structure analysis, facilitating detailed investigations and yielding valuable insights.
I highly recommend the LGALS9 protein for various experimental applications.
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