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Recombinant Human PLG Protein, Fc Chimera

Cat.No.: PLG-1107H
Product Overview: Recombinant Human PLG (Accession # P00747), fused with , was produced in Mouse myeloma cell line, NS0-derived.
Source: NSO Cells
Species: Human
Tag: Fc
Predicted N Terminal: Met-Asp-Pro100
Form: Lyophilized from a 0.2 µm filtered solution in PBS.
Bio-activity: Measured by the ability of the immobilized protein to support the adhesion of THP-1 human acute monocytic leukemia cells. Chavakis, T. et al. (2005) Blood 10^5:1036.The ED50 for this effect is typically 0.5-2.5 µg/mL.
Molecular Mass: Recombinant Human PLG, Fc Chimera has a calculated MW of 67.7 kDa (monomer). In SDS-PAGE migrates as 75-85 kDa, reducing conditions.
Purity: >95%, by SDS-PAGE with silver staining, under reducing conditions.
Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name: PLG plasminogen [ Homo sapiens ]
Official Symbol: PLG
Synonyms: PLG; plasminogen; plasmin; DKFZp779M0222;
Gene ID: 5340
mRNA Refseq: NM_001168338
Protein Refseq: NP_001161810
MIM: 173350
UniProt ID: P00747
Chromosome Location: 6q26

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