Recombinant Human PLG Protein, Fc Chimera

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Recombinant Human PLG Protein, Fc Chimera

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Cat.No. : PLG-1107H
Product Overview : Recombinant Human PLG (Accession # P00747), fused with , was produced in Mouse myeloma cell line, NS0-derived.
Source : NSO Cells
Species : Human
Tag : Fc
Predicted N Terminal : Met-Asp-Pro100
Form : Lyophilized from a 0.2 µm filtered solution in PBS.
Bio-activity : Measured by the ability of the immobilized protein to support the adhesion of THP-1 human acute monocytic leukemia cells. Chavakis, T. et al. (2005) Blood 10^5:1036.The ED50 for this effect is typically 0.5-2.5 µg/mL.
Molecular Mass : Recombinant Human PLG, Fc Chimera has a calculated MW of 67.7 kDa (monomer). In SDS-PAGE migrates as 75-85 kDa, reducing conditions.
Purity : >95%, by SDS-PAGE with silver staining, under reducing conditions.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name : PLG plasminogen [ Homo sapiens ]
Official Symbol : PLG
Synonyms : PLG; plasminogen; plasmin; DKFZp779M0222;
Gene ID : 5340
mRNA Refseq : NM_001168338
Protein Refseq : NP_001161810
MIM : 173350
UniProt ID : P00747
Chromosome Location : 6q26

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