Recombinant Human CCNG1, His-tagged

• Cat.No.: CCNG1-26094TH
• Product Overview: Recombinant full length Human Cyclin G with an N-terminal His tag. 315 amino acides with a predicted MWt34 kDa including the tag

Specification

• Description: The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The protein encoded by this gene is a member of the cyclin family and contains the cyclin box. The encoded protein lacks the protein destabilizing (PEST) sequence that is present in other family members. Transcriptional activation of this gene can be induced by tumor protein p53. Two transcript variants encoding the same protein have been identified for this gene.
• Protein length: 295 amino acids
• Conjugation: HIS
• Molecular Weight: 36.200kDa inclusive of tags
• Source: E. coli
• Tissue specificity: High levels in skeletal muscle, ovary, kidney and colon.
• Form: Liquid
• Purity: by SDS-PAGE
• Storage buffer: pH: 8.00Constituents:1.17% Sodium chloride, 0.08% DTT, 50% Glycerol, 0.32% Tris HCl
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHHSSGLVPRGSHMIEVLTTTDSQKLLHQLNAL LEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLL SLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLS CFYLAVKSIEEERNVPLATDLIRISQYRFTVSDLMRMEKI VLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFE RLEAQLKACHCRIIFSKAKPSVLALSIIALEIQAQKCVEL TEGIECLQKHSKINGRDLTFWQELVSKCLTEYSSNKCSKP NVQKLKWIVSGRTARQLKHSYYRITHLPTIPEMVP
• Sequence Similarities: Belongs to the cyclin family. Cyclin G subfamily.

Gene Information

• Gene Name: CCNG1 cyclin G1 [ Homo sapiens ]
• Official Symbol: CCNG1
• Synonyms: CCNG1; cyclin G1; CCNG; cyclin-G1
• Gene ID: 900
• mRNA Refseq: NM_004060
• Protein Refseq: NP_004051
• MIM: 601578
• Uniprot ID: P51959
• Chromosome Location: 5q32-q34
• Pathway: Direct p53 effectors, organism-specific biosystem; p53 pathway, organism-specific biosystem; p53 signaling pathway, organism-specific biosystem; p53 signaling pathway, conserved biosystem
• Function: protein domain specific binding