Recombinant Human CSRP3, T7 -tagged
Cat.No. : | CSRP3-26431TH |
Product Overview : | Recombinant full length protein, Human CSRP3 with an N-terminal T7 tag. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5 UTR, but encoding the same protein, have been found for this gene. |
Conjugation : | T7 |
Source : | E. coli |
Tissue specificity : | Cardiac and slow-twitch skeletal muscles. |
Form : | Liquid |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: 0.002% Sodium AzideConstituents: 10mM Tris, 10mM DTT, 0.1% Triton X-100, pH 8.0 |
Storage : | Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles. |
Sequence Similarities : | Contains 2 LIM zinc-binding domains. |
Gene Name : | CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) [ Homo sapiens ] |
Official Symbol : | CSRP3 |
Synonyms : | CSRP3; cysteine and glycine-rich protein 3 (cardiac LIM protein); cysteine and glycine-rich protein 3; CLP; CMD1M; MLP; |
Gene ID : | 8048 |
mRNA Refseq : | NM_001127656 |
Protein Refseq : | NP_001121128 |
MIM : | 600824 |
Uniprot ID : | P50461 |
Chromosome Location : | 11p15.1 |
Function : | metal ion binding; protein binding; zinc ion binding; |
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◆ Lysates | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionThere is emerging interest in exploring the potential of CSRP3 in regenerative medicine, particularly in the context of muscle regeneration and repair.
Potential therapeutic strategies may involve gene therapy, small molecule inhibitors, or other approaches aimed at modulating the function of CSRP3.
Genetic variations in the CSRP3 gene have been linked to certain cardiac and muscular disorders, providing insights into disease susceptibility.
CSRP3 has been implicated in skeletal muscle disorders, such as muscular dystrophy, suggesting its relevance in potential therapeutic interventions.
One challenge is understanding the precise mechanisms by which CSRP3 contributes to disease pathogenesis and how best to modulate its function.
Customer Reviews (3)
Write a reviewThe CSRP3 Protein comes highly recommended for its exceptional performance, particularly in ELISA assays.
Researchers utilizing the CSRP3 Protein can rely on its robust and reproducible performance in a variety of experimental settings.
This protein has proven to be of great utility in protein electron microscopy structure analysis.
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