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Recombinant Human CSRP3, T7 -tagged

Cat.No. : CSRP3-26431TH
Product Overview : Recombinant full length protein, Human CSRP3 with an N-terminal T7 tag.
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Description : This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5 UTR, but encoding the same protein, have been found for this gene.
Conjugation : T7
Source : E. coli
Tissue specificity : Cardiac and slow-twitch skeletal muscles.
Form : Liquid
Purity : >95% by SDS-PAGE
Storage buffer : Preservative: 0.002% Sodium AzideConstituents: 10mM Tris, 10mM DTT, 0.1% Triton X-100, pH 8.0
Storage : Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Sequence Similarities : Contains 2 LIM zinc-binding domains.
Gene Name : CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) [ Homo sapiens ]
Official Symbol : CSRP3
Synonyms : CSRP3; cysteine and glycine-rich protein 3 (cardiac LIM protein); cysteine and glycine-rich protein 3; CLP; CMD1M; MLP;
Gene ID : 8048
mRNA Refseq : NM_001127656
Protein Refseq : NP_001121128
MIM : 600824
Uniprot ID : P50461
Chromosome Location : 11p15.1
Function : metal ion binding; protein binding; zinc ion binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can CSRP3 protein be used in regenerative medicine applications? 01/13/2023

There is emerging interest in exploring the potential of CSRP3 in regenerative medicine, particularly in the context of muscle regeneration and repair.

What potential therapeutic strategies involve targeting CSRP3 protein? 05/18/2021

Potential therapeutic strategies may involve gene therapy, small molecule inhibitors, or other approaches aimed at modulating the function of CSRP3.

Are there any genetic variations in the CSRP3 gene associated with disease susceptibility? 06/21/2019

Genetic variations in the CSRP3 gene have been linked to certain cardiac and muscular disorders, providing insights into disease susceptibility.

How does CSRP3 protein relate to skeletal muscle diseases? 11/26/2018

CSRP3 has been implicated in skeletal muscle disorders, such as muscular dystrophy, suggesting its relevance in potential therapeutic interventions.

Are there any challenges in targeting CSRP3 for clinical applications? 05/27/2017

One challenge is understanding the precise mechanisms by which CSRP3 contributes to disease pathogenesis and how best to modulate its function.

Customer Reviews (3)

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Reviews
12/23/2022

    The CSRP3 Protein comes highly recommended for its exceptional performance, particularly in ELISA assays.

    01/06/2021

      Researchers utilizing the CSRP3 Protein can rely on its robust and reproducible performance in a variety of experimental settings.

      05/18/2017

        This protein has proven to be of great utility in protein electron microscopy structure analysis.

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