Recombinant Human FXR2, His-tagged

• Cat.No.: FXR2-26270TH
• Product Overview: Recombinant fragment, corresponding to amino acids 217-512 of Human FXR2 with N terminal His tag; 296 amino acids, 34kDa.

Specification

• Description: The protein encoded by this gene is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X mental retardation syndrome.
• Conjugation: HIS
• Source: E. coli
• Form: Lyophilised:Reconstitute with 117 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Store at 4°C. Upon reconstitution store at -80oC.
• Sequences of amino acids: KHLETSKQLAAAFQEEFTVREDLMGLAIGTHGANIQQARK VPGVTAIELGEETCTFRIYGETPEACRQARSYLEFSED SVQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRVEGDNDK KNPREEGMVPFIFVGTRENISNAQALLEYHLSYLQEVE QLRLERLQIDEQLRQIGLGFRPPGSGRGSGGSDKAGYS TDESSSSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSDVS TASETESEKREEPNRAGPGDRDPPTRGEESRRRPTGGR GRGPPPAPRPTSRYNSSSISSVLK
• Sequence Similarities: Belongs to the FMR1 family.Contains 2 KH domains.

Gene Information

• Gene Name: FXR2 fragile X mental retardation, autosomal homolog 2 [ Homo sapiens ]
• Official Symbol: FXR2
• Synonyms: FXR2; fragile X mental retardation, autosomal homolog 2; FMR1L2; fragile X mental retardation syndrome-related protein 2
• Gene ID: 9513
• mRNA Refseq: NM_004860
• Protein Refseq: NP_004851
• MIM: 605339
• Uniprot ID: P51116
• Chromosome Location: 17p13.3
• Pathway: RNA transport, organism-specific biosystem; RNA transport, conserved biosystem
• Function: RNA binding; protein binding