Recombinant Human GATM
Cat.No. : | GATM-28986TH |
Product Overview : | Recombinant fragment of Human GATM with an N-terminal proprietary tag; Predicted MW 36.63kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders. |
Protein length : | 100 amino acids |
Molecular Weight : | 36.630kDa inclusive of tags |
Source : | Wheat germ |
Tissue specificity : | Expressed in brain, heart, kidney, liver, lung, salivary gland and skeletal muscle tissue, with the highest expression in kidney. Biallelically expressed in placenta and fetal tissues. |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | MLRVRCLRGGSRGAEAVHYIGSRLGRTLTGWVQRTFQSTQ AATASSRNSCAADDKATEPLPKDCPVSSYNEWDPLEEVIV GRAENACVPPFTIEVKANTY |
Sequence Similarities : | Belongs to the amidinotransferase family. |
Gene Name : | GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) [ Homo sapiens ] |
Official Symbol : | GATM |
Synonyms : | GATM; glycine amidinotransferase (L-arginine:glycine amidinotransferase); glycine amidinotransferase, mitochondrial; AGAT; |
Gene ID : | 2628 |
mRNA Refseq : | NM_001482 |
Protein Refseq : | NP_001473 |
MIM : | 602360 |
Uniprot ID : | P50440 |
Chromosome Location : | 15q15.1 |
Pathway : | Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; Creatine metabolism, organism-specific biosystem; Creatine pathway, organism-specific biosystem; Creatine pathway, conserved biosystem; |
Function : | glycine amidinotransferase activity; glycine amidinotransferase activity; transferase activity; |
Products Types
◆ Recombinant Protein | ||
GATM-4761H | Recombinant Human GATM Protein, GST-tagged | +Inquiry |
GATM-2141R | Recombinant Rat GATM Protein, His (Fc)-Avi-tagged | +Inquiry |
GATM-965H | Recombinant Human GATM Protein, His (Fc)-Avi-tagged | +Inquiry |
GATM-3489M | Recombinant Mouse GATM Protein, His (Fc)-Avi-tagged | +Inquiry |
Gatm-3164M | Recombinant Mouse Gatm Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
GATM-6005HCL | Recombinant Human GATM 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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