"GHR" Related Products

Expand
Expand
Expand

Recombinant Human Growth Hormone Receptor

Cat. No.: GHR-1623H
Description: Growth hormone receptor, also known as GHR is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature (proportional dwarfism).
Source: NSO Cells.
State Of Matter: Lyophilized.
Purity: >90% by SDS Page and analyzed by silver stain.
Endotoxin: <1.0 EU/µg as determined by the LAL method.
Molecular Weight: The predicted molecular weight of Recombinant Human GHR is Mr 54 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 75-90 kDa.
Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Gene Name: GHR growth hormone receptor [ Homo sapiens ]
Synonyms: GHBP; GH receptor; Somatotropin receptor; GH receptor; Somatotropin receptor; growth hormone binding protein; growth hormone receptor; serum binding protein; GHR
Gene ID: 2690
mRNA Refseq: NM_000163
Protein Refseq: NP_000154
MIM: 600946
UniProt ID: P10912
Chromosome Location: 5p14-p12
Pathway: Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway; Neuroactive ligand-receptor interaction
Function: SH2 domain binding; growth hormone receptor activity; peptide hormone binding; receptor activity; phosphate binding; proline-rich region binding; protein kinase binding; protein homodimerization activity; protein phosphatase binding

Online Inquiry

Note: There will be extra charge for optional service!
Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information


Price does not include shipping and packaging costs.Request quote for final price.

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.