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Recombinant Mouse Granzyme B

Cat. No.: Gzmb-414M
Description: Granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1), also known as GZMB, is a serine protease involved in many pathologies, including viral infections, autoimmunity, transplant rejection, and antitumor immunity. Granzyme B may be a useful prognostic marker in early rheumatoid arthritis and may provide important clues to the pathogenesis of this disease.
Source: NSO cells.
Molecular Weight: The molecular weight of Recombinant Mouse Granzyme B is 34-37 kDa.
State Of Matter: Lyophilized.
Purity: >95% by SDS Page and analyzed by silver stain.
Endotoxin: <1.0 EU/µg as determined by the LAL method.
Storage: This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Gene Name: Gzmb granzyme B [ Mus musculus ]
Synonyms: Gzmb; granzyme B; GZB; CCP1; Ctla1; Ctla-1; AI553453; CCP-1; C11
Gene ID: 14939
mRNA Refseq: NM_013542
Protein Refseq: NP_038570
UniProt ID: P04187
Chromosome Location: 14
Pathway: Allograft rejection; Autoimmune thyroid disease; Graft-versus-host disease; Natural killer cell mediated cytotoxicity; Type I diabetes mellitus
Function: catalytic activity; hydrolase activity; peptidase activity; protein binding; serine-type endopeptidase activity; serine-type peptidase activity

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