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Recombinant Mouse Granzyme B

Cat. No. : Gzmb-414M
Description : Granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1), also known as GZMB, is a serine protease involved in many pathologies, including viral infections, autoimmunity, transplant rejection, and antitumor immunity. Granzyme B may be a useful prognostic marker in early rheumatoid arthritis and may provide important clues to the pathogenesis of this disease.
Source : NSO cells.
Molecular Weight : The molecular weight of Recombinant Mouse Granzyme B is 34-37 kDa.
State Of Matter : Lyophilized.
Purity : >95% by SDS Page and analyzed by silver stain.
Endotoxin : <1.0 EU/µg as determined by the LAL method.
Storage : This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
PDB rendering based on 1fq3. :

Gene Name : Gzmb granzyme B [ Mus musculus ]
Synonyms : Gzmb; granzyme B; GZB; CCP1; Ctla1; Ctla-1; AI553453; CCP-1; C11
Gene ID : 14939
mRNA Refseq : NM_013542
Protein Refseq : NP_038570
UniProt ID : P04187
Chromosome Location : 14
Pathway : Allograft rejection; Autoimmune thyroid disease; Graft-versus-host disease; Natural killer cell mediated cytotoxicity; Type I diabetes mellitus
Function : catalytic activity; hydrolase activity; peptidase activity; protein binding; serine-type endopeptidase activity; serine-type peptidase activity

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