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Recombinant Human RBM5, His-tagged

Cat.No. : RBM5-31232TH
Product Overview : Recombinant fragment, corresponding to amino acids 582-815 of Human RBM5 with an N terminal His tag. Observed mwt: 33 kDa.
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  • Gene Information
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Description : This gene is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex. The encoded protein plays a role in the induction of cell cycle arrest and apoptosis through pre-mRNA splicing of multiple target genes including the tumor suppressor protein p53. This gene is located within the tumor suppressor region 3p21.3, and may play a role in the inhibition of tumor transformation and progression of several malignancies including lung cancer.
Conjugation : HIS
Source : E. coli
Form : Lyophilised:Reconstitute with 70 μl aqua dest.
Storage buffer : Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
Storage : Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : GFALFEKKGALAERQQLIPELVRNG DEENPLKRGLVAAYS GDSDNEEELVERLESEEEKLADWKK MACLLCRRQFPNK DALVRHQQLSDLHKQNMDIYRRSRL SEQELEALELREREMKYRDRAAERR EKYGIPEPPEPKRKKQFDAGTVNYE QPT KDGIDHSNIGNKMLQAMGWREGSGL GRKCQGITAPIEA QVRLKGAGLGAKGSAYGLSGADSYK DAVRKAMFARFTEME
Gene Name : RBM5 RNA binding motif protein 5 [ Homo sapiens ]
Official Symbol : RBM5
Synonyms : RBM5; RNA binding motif protein 5; RNA-binding protein 5; H37; LUCA15;
Gene ID : 10181
mRNA Refseq : NM_005778
Protein Refseq : NP_005769
MIM : 606884
Uniprot ID : P52756
Chromosome Location : 3p21.3
Pathway : Formation and Maturation of mRNA Transcript, organism-specific biosystem; Gene Expression, organism-specific biosystem; Processing of Capped Intron-Containing Pre-mRNA, organism-specific biosystem; mRNA Processing, organism-specific biosystem; mRNA Splicing, organism-specific biosystem;
Function : DNA binding; RNA binding; mRNA binding; metal ion binding; nucleotide binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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