Recombinant Human SGCG
Cat.No. : | SGCG-26403TH |
Product Overview : | Recombinant fragment corresponding to amino acids 191-290 of Human gamma Sarcoglycan with an N terminal proprietary tag; Predicted MWt 36.63 kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C). |
Protein length : | 100 amino acids |
Molecular Weight : | 36.630kDa inclusive of tags |
Source : | Wheat germ |
Tissue specificity : | Expressed in skeletal and heart muscle. |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | DLRLESPTRSLSMDAPRGVHIQAHA GKIEALSQMDILFHSSDGMLVLDAE TVCLPKLVQGTWGPSGSSQSLYEIC VCPDGKLYLSVAGVSTTCQEHSHIC |
Sequence Similarities : | Belongs to the sarcoglycan beta/delta/gamma/zeta family. |
Gene Name : | SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) [ Homo sapiens ] |
Official Symbol : | SGCG |
Synonyms : | SGCG; sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein); DMDA1, LGMD2C, MAM, sarcoglycan, gamma (35kD dystrophin associated glycoprotein); gamma-sarcoglycan; 35kD dystrophin associated glycoprotein; A4; DAGA4; DMDA; gamma sarcoglycan; limb gi |
Gene ID : | 6445 |
mRNA Refseq : | NM_000231 |
Protein Refseq : | NP_000222 |
MIM : | 608896 |
Uniprot ID : | Q13326 |
Chromosome Location : | 13q12-q13 |
Pathway : | Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Dilated cardiomyopathy, organism-specific biosystem; Dilated cardiomyopathy, conserved biosystem; Hypertrophic cardiomyopathy (HCM), organism-specific biosystem; |
Products Types
◆ Recombinant Protein | ||
SGCG-1996H | Recombinant Human SGCG Protein, His (Fc)-Avi-tagged | +Inquiry |
SGCG-8099M | Recombinant Mouse SGCG Protein, His (Fc)-Avi-tagged | +Inquiry |
SGCG-359H | Recombinant Human SGCG Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
Sgcg-5822M | Recombinant Mouse Sgcg Protein, Myc/DDK-tagged | +Inquiry |
SGCG-15032M | Recombinant Mouse SGCG Protein | +Inquiry |
◆ Lysates | ||
SGCG-1887HCL | Recombinant Human SGCG 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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