"SOX9" Related Products


Recombinant Human SOX9

Cat.No.: SOX9-30695TH
Product Overview: Recombinant fragment of Human SOX9 fused to a proprietary tag, 48kDa.
Description: The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.
Protein length: 194 amino acids
Molecular Weight: 48.000kDa inclusive of tags
Source: E. coli
Form: Liquid
Purity: Proprietary Purification
Storage buffer: pH: 7.50Constituents:20% Glycerol, Tris acetate, 0.03% EDTA
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sequence Similarities: Contains 1 HMG box DNA-binding domain.
Gene Name: SOX9 SRY (sex determining region Y)-box 9 [ Homo sapiens ]
Official Symbol: SOX9
Synonyms: SOX9; SRY (sex determining region Y)-box 9; campomelic dysplasia, autosomal sex reversal , CMD1, CMPD1; transcription factor SOX-9; SRA1;
Gene ID: 6662
mRNA Refseq: NM_000346
Protein Refseq: NP_000337
MIM: 608160
Uniprot ID: P48436
Chromosome Location: 17q23
Pathway: Endochondral Ossification, organism-specific biosystem; Wnt Signaling Pathway NetPath, organism-specific biosystem;
Function: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; beta-catenin binding; chromatin binding; core promoter sequence-specific DNA binding; enhancer bi;

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