Recombinant Human Nuclear Transport Factor 2, His-tagged

• Cat.No.: NUTF2-2566H
• Product Overview: Recombinant human NUTF2, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography. MW =16.6 kDa(147aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: NUTF2 is a cytosolic factor that facilitates protein transport into the nucleus. It interacts with the nuclear pore complex glycoprotein p62 and Ran. This protein acts at a relative late stage of nuclear protein import, subsequent to the initial docking of nuclear import ligand at the nuclear envelope. It binds directly to RanGDP and may modulate the steady-state distribution of Ran.
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MGDKPIWEQI GSSFIQHYYQ LFDNDRTQLG AIYIDASCLT WEGQQFQGKA AIVEKLSSLP FQKIQHSITA QDHQPTPDSC IISMVVGQLK ADEDPIMGFH QMFLLKNIND AWVCTNDMFR LALHNFG
• Purity: > 95% by SDS – PAGE.
• Form: Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 10% Glycerol.
• Concentration: 1 mg/ml (determined by Bradford assay).
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Publications:
  The pseudorabies virus DNA polymerase accessory subunit UL42 directs nuclear transport of the holoenzym (2016)

Gene Information

• Gene Name: NUTF2 nuclear transport factor 2 [ Homo sapiens ]
• Synonyms: NUTF2; nuclear transport factor 2; NTF2; PP15; NTF-2; placental protein 15
• Gene ID: 10204
• mRNA Refseq: NM_005796
• Protein Refseq: NP_005787
• MIM: 605813
• UniProt ID: P61970
• Chromosome Location: 16q22.1
• Function: protein binding; protein transporter activity; transporter activity