Nodularin Analytical Standard

• Cat.No.: NOD-10N
• Product Overview: Cyclic pentapeptide toxin isolated from the freshwater cyanobacterium Nodularia sp. The identity of the compound has been confirmed by NMR and MS/MS. The analytical standard is dissolved in 100% methanol and ready to use for calibration. It is distributed in amber glass vials containing around 10 μg in 1 mL MeOH. The concentration of each lot is determined spectrophotometrically, confirmed by HPLC, and stated on the Certificate of Analysis.

Specification

• Species: Nodularia sp.
• Source: Nodularia sp.
• Form: Solution
• Molecular Formula: C41H60N8O10
• Molecular Weight: 824,4 g/mol
• Purity: >95 % (HPLC)
• Long Term Storage: At - 20 centigrade.
• Shelf life: 24 months
• Stability: The analytical standard should be used immediately after the vial is opened
• Buffer: Solution of 10 μg/mL in methanol
• Concentration: 10 μg/mL
• Shipping: Ambient
• Note: For research use only!
• References: 1. Rinehart et al., Nodularin, microcystin and the configuration of Adda, J. Am. Chem. Soc. 1988, 110, 8557-8558
  2. Namikoshi et al., New Nodularins: A General Method for Structure Assignment, J. Org. Chem. 1994, 59, 2349-2357
  3. Honkanen et al., Cyanobacterial nodularin is a potent inhibitor of type 1 and type 2A protein phosphatases, Mol. Pharmacol. 1991, 40, 577-583
  4. Lankoff et al., Nodularin-induced genotoxicity following oxidative DNA damage and aneuploidy in HepG2 cells, Toxicl. Lett. 2006, 164, 239-248

Gene Information

• Official Symbol: NOD
• Synonyms: NOD; Nodularin