Recombinant Full Length Human CFL1 Protein, C-Flag-tagged
Cat.No. : | CFL1-1692HFL |
Product Overview : | Recombinant Full Length Human CFL1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 18.3 kDa |
AA Sequence : | MASGVAVSDGVIKVFNDMKVRKSST PEEVKKRKKAVLFCLSEDKKNIILE EGKEILVGDVGQTVDDPYAT FVKMLPDKDCRYALYDATYETKESK KEDLVFIFWAPESAPLKSKMIYASS KDAIKKKLTGIKHELQANCY EEVKDRCTLAEKLGGSAVISLEGKP LTRTRPLEQKLISEEDLAANDILDY KDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome |
Protein Pathways : | Axon guidance, Fc gamma R-mediated phagocytosis, Regulation of actin cytoskeleton |
Gene Name : | CFL1 cofilin 1 [ Homo sapiens (human) ] |
Official Symbol : | CFL1 |
Synonyms : | CFL; cofilin; HEL-S-15 |
Gene ID : | 1072 |
mRNA Refseq : | NM_005507.3 |
Protein Refseq : | NP_005498.1 |
MIM : | 601442 |
UniProt ID : | P23528 |
Products Types
◆ Recombinant Protein | ||
CFL1-1614M | Recombinant Mouse CFL1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CFL1-654R | Recombinant Rhesus Macaque CFL1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CFL1-768H | Recombinant Human CFL1 Protein, His-tagged | +Inquiry |
CFL1-1172H | Recombinant Human CFL1 Protein, GST-Tagged | +Inquiry |
CFL1-0152H | Recombinant Human CFL1 Protein (M1-L166), His/Step tagged | +Inquiry |
◆ Lysates | ||
CFL1-7555HCL | Recombinant Human CFL1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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