Recombinant Full Length Human CHAC2 Protein, C-Flag-tagged

• Cat.No.: CHAC2-1084HFL
• Product Overview: Recombinant Full Length Human CHAC2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene is a gamma-glutamyl cyclotransferase that catalyzes the conversion of glutathione to 5-oxoproline and cysteinylglycine. It is thought that this gene is upregulated in response to endoplasmic reticulum stress and that the glutathione depletion enhances apoptosis.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 20.7 kDa
• AA Sequence: MWVFGYGSLIWKVDFPYQDKLVGYI TNYSRRFWQGSTDHRGVPGKPGRVV TLVEDPAGCVWGVAYRLPVG KEEEVKAYLDFREKGGYRTTTVIFY PKDPTTKPFSVLLYIGTCDNPDYLG PAPLEDIAEQIFNAAGPSGR
  NTEYLFELANSIRNLVPEEADEHLF ALEKLVKERLEGKQNLNCITRTRPL EQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: CHAC2 ChaC glutathione specific gamma-glutamylcyclotransferase 2 [ Homo sapiens (human) ]
• Official Symbol: CHAC2
• Synonyms: GCG1
• Gene ID: 494143
• mRNA Refseq: NM_001008708.4
• Protein Refseq: NP_001008708.1
• MIM: 617446
• UniProt ID: Q8WUX2