Recombinant Full Length Human PROKR1 Protein, C-Flag-tagged

• Cat.No.: PROKR1-1902HFL
• Product Overview: Recombinant Full Length Human PROKR1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the G-protein-coupled receptor family. The encoded protein binds to prokineticins (1 and 2), leading to the activation of MAPK and STAT signaling pathways. Prokineticins are protein ligands involved in angiogenesis and inflammation. The encoded protein is expressed in peripheral tissues such as those comprising the circulatory system, lungs, reproductive system, endocrine system and the gastrointestinal system. The protein may be involved in signaling in human fetal ovary during initiation of primordial follicle formation. Sequence variants in this gene may be associated with recurrent miscarriage.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 44.6 kDa
• AA Sequence: METTMGFMDDNATNTSTSFLSVLNP HGAHATSFPFNFSYSDYDMPLDEDE DVTNSRTFFAAKIVIGMALV GIMLVCGIGNFIFIAALVRYKKLRN LTNLLIANLAISDFLVAIVCCPFEM DYYVVRQLSWEHGHVLCTSV NYLRTVSLYVSTNALLAIAIDRYLA IVHPLRPRMKCQTATGLIALVWTVS ILIAIPSAYFTTETVLVIVK SQEKIFCGQIWPVDQQLYYKSYFLF IFGIEFVGPVVTMTLCYARISRELW FKAVPGFQTEQIRKRLRCRR KTVLVLMCILTAYVLCWAPFYGFTI VRDFFPTVFVKEKHYLTAFYIVECI AMSNSMINTLCFVTVKNDTV KYFKKIMLLHWKASYNGGKSSADLD LKTIGMPATEEVDCIRLK TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, GPCR, Transmembrane

Gene Information

• Gene Name: PROKR1 prokineticin receptor 1 [ Homo sapiens (human) ]
• Official Symbol: PROKR1
• Synonyms: ZAQ; PKR1; GPR73; PK-R1; GPR73a
• Gene ID: 10887
• mRNA Refseq: NM_138964.4
• Protein Refseq: NP_620414.1
• MIM: 607122
• UniProt ID: Q8TCW9