Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human DHRS9 Protein, GST-tagged

Cat.No. : DHRS9-2603H
Product Overview : Human DHRS9 full-length ORF ( AAH58883, 1 a.a. - 319 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. This protein demonstrates oxidoreductase activity toward hydroxysteroids and is able to convert 3-alpha-tetrahydroprogesterone to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone in the cytoplasm, and may additionally function as a transcriptional repressor in the nucleus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 60.83 kDa
AA Sequence : MLFWVLGLLILCGFLWTRKGKLKIE DITDKYIFITGCDSGFGNLAARTFD KKGFHVIAACLTESGSTALKAETSE RLRTVLLDVTDPENVKRTAQWVKNQ VGEKGLWGLINNAGVPGVLAPTDWL TLEDYREPIEVNLFGLISVTLNMLP LVKKAQGRVINVSSVGGRLAIVGGG YTPSKYAVEGFNDSLRRDMKAFGVH VSCIEPGLFKTNLADPVKVIEKKLA IWEQLSPDIKQQYGEGYIEKSLDKL KGNKSYVNMDLSPVVECMDHALTSL FPKTHYAAGKDAKIFWIPLSHMPAA LQDFLLLKQKAELANPKAV
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : DHRS9 dehydrogenase/reductase (SDR family) member 9 [ Homo sapiens ]
Official Symbol : DHRS9
Synonyms : DHRS9; dehydrogenase/reductase (SDR family) member 9; dehydrogenase/reductase SDR family member 9; 3 alpha hydroxysteroid dehydrogenase; 3alpha HSD; NADP dependent retinol dehydrogenase/reductase; RDH15; RDHL; retinol dehydrogenase homolog; RETSDR8; SDR9C4; short chain dehydrogenase/reductase family 9C; member 4; RDH-E2; 3-alpha-HSD; 3-alpha hydroxysteroid dehydrogenase; short-chain dehydrogenase/reductase retSDR8; NADP-dependent retinol dehydrogenase/reductase; short chain dehydrogenase/reductase family 9C, member 4; RDHTBE; 3ALPHA-HSD;
Gene ID : 10170
mRNA Refseq : NM_001142270
Protein Refseq : NP_001135742
MIM : 612131
UniProt ID : Q9BPW9

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (6)

Ask a question
Can lifestyle changes reduce the risk for DHRS9 mutations? 11/19/2022

There is currently no definitive way to alter the variation of the DHRS9 gene. However, healthy lifestyles, such as a balanced diet, moderate exercise, and good social interactions, may help reduce the risk of neurological disorders, although they may not directly improve the effects of the DHRS9 gene variant.

What is the effect of mutations in the DHRS9 gene? 11/16/2022

Mutations in the DHRS9 gene may cause abnormal function of retinoic acid-binding protein 1, which in turn affects retinoic acid metabolism and may increase the risk of neurological diseases.

Are DHRS9 gene variants associated with cognitive function 08/31/2022

Studies have shown that mutations in the DHRS9 gene may affect cognitive function, but the specific mechanism still needs further research.

What might be involved in future studies of the DHRS9 gene? 08/05/2022

Future research on the DHRS9 gene may involve more in-depth studies of molecular mechanisms, disease associations, and the development of therapeutics for this gene variant.

Are variants in the DHRS9 gene associated with behavioral traits? 07/04/2022

Studies have shown that mutations in the DHRS9 gene may be associated with certain behavioral traits, such as social skills, attention, and impulse control.

How to detect variants in the DHRS9 gene? 04/16/2020

Variants in the DHRS9 gene, including single nucleotide polymorphisms (SNPs), insertions/deletions, etc., can be detected by gene sequencing technology.

Customer Reviews (3)

Write a review
Reviews
10/24/2022

    DHRS9 is highly specific and active, and does not cause abnormal immune responses.

    04/22/2022

      The product is very mature and can be used for scientific research.

      10/19/2020

        The solubility is very good and can be easily dissolved in a variety of buffers.

        Ask a Question for All DHRS9 Products

        Required fields are marked with *

        My Review for All DHRS9 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends