Recombinant Human JAG1 Protein, His-tagged

Cat.No. : JAG1-2348H
Product Overview : Recombinant Human JAG1 Protein (Gly33-Asp250) with a N-His tag was expressed in E. coli.
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Species : Human
Source : E.coli
Tag : His
ProteinLength : Gly33-Asp250
Description : The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter is involved in signaling processes. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 28.0 kDa
Accurate Molecular Mass: \
Endotoxin : <1.0 EU per 1µg (determined by the LAL method).
Purity : > 90%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Storage Buffer : 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Reconstitution : Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Gene Name JAG1 jagged 1 [ Homo sapiens (human) ]
Official Symbol JAG1
Synonyms JAG1; jagged 1; AGS, Alagille syndrome, JAGL1; protein jagged-1; AHD; AWS; CD339; HJ1; AGS; JAGL1; MGC104644;
Gene ID 182
mRNA Refseq NM_000214
Protein Refseq NP_000205
MIM 601920
UniProt ID P78504

Not For Human Consumption!

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