| Description : |
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter is involved in signaling processes. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
His |
| Form : |
Lyophilized |
| Molecular Mass : |
112.3 kDa |
| Protein Length : |
1218 |
| AA Sequence : |
MRSPRTRGRSGRPLSLLLALLCALR AKVCGASGQFELEILSMQNVNGELQ NGNCCGGARNPGDRKCTRDECDTYF KVCLKEYQSRVTAGGPCSFGSGSTP VIGGNTFNLKASRGNDRNRIVLPFS FAWPRSYTLLVEAWDSSNDTVQPDS IIEKASHSGMINPSRQWQTLKQNTG VAHFEYQIRVTCDDYYYGFGCNKFC RPRDDFFGHYACDQNGNKTCMEGWM GPECNRAICRQGCSPKHGSCKLPGD CRCQYGWQGLYCDKCIPHPGCVHGI CNEPWQCLCETNWGGQLCDKDLNYC GTHQPCLNGGTCSNTGPDKYQCSCP EGYSGPNCEIAEHACLSDPCHNRGS CKETSLGFECECSPGWTGPTCSTNI DDCSPNNCSHGGTCQDLVNGFKCVC PPQWTGKTCQLDANECEAKPCVNAK SCKNLIASYYCDCLPGWMGQNCDIN INDCLGQCQNDASCRDLVNGYRCIC PPGYAGDHCERDIDECASNPCLNGG HCQNEINRFQCLCPTGFSGNLCQLD IDYCEPNPCQNGAQCYNRASDYFCK CPEDYEGKNCSHLKDHCRTTPCEVI DSCTVAMASNDTPEGVRYISSNVCG PHGKCKSQSGGKFTCDCNKGFTGTY CHENINDCESNPCRNGGTCIDGVNS YKCICSDGWEGAYCETNINDCSQNP CHNGGTCRDLVNDFYCDCKNGWKGK TCHSRDSQCDEATCNNGGTCYDEGD AFKCMCPGGWEGTTCNIARNSSCLP NPCHNGGTCVVNGESFTCVCKEGWE GPICAQNTNDCSPHPCYNSGTCVDG DNWYRCECAPGFAGPDCRININECQ SSPCAFGATCVDEINGYRCVCPPGH SGAKCQEVSGRPCITMGSVIPDGAK WDDDCNTCQCLNGRIACSKVWCGPR PCLLHKGHSECPSGQSCIPILDDQC FVHPCTGVGECRSSSLQPVKTKCTS DSYYQDNCANITFTFNKEMMSPGLT TEHICSELRNLNILKNVSAEYSIYI ACEPSPSANNEIHVAISAEDIRDDG NPIKEITDKIIDLVSKRDGNSSLIA AVAEVRVQRRPLKNRTDFLVPLLSS VLTVAWICCLVTAFYWCLRKRRKPG SHTHSASEDNTTNNVREQLNQIKNP IEKHGANTVPIKDYENKNSKMSKIR THNSEVEEDDMDKHQQKARFAKQPA YTLVDREEKPPNGTPTKHPNWTNKQ DNRDLESAQSLNRMEYIV |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
