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Recombinant Human PMM2 Protein, Myc/DDK-tagged, C13 and N15-labeled
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Cat.No. : | PMM2-6090H |
Product Overview : | PMM2 MS Standard C13 and N15-labeled recombinant protein (NP_000294) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
Description : | The protein encoded by this gene catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, which is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. Mutations in this gene have been shown to cause defects in glycoprotein biosynthesis, which manifests as carbohydrate-deficient glycoprotein syndrome type I. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 27.9 kDa |
AA Sequence : | MAAPGPALCL FDVDGTLTAP RQKITKEMDD FLQKLRQKIK IGVVGGSDFE KVQEQLGNDV VEKYDYVFPE NGLVAYKDGK LLCRQNIQSH LGEALIQDLI NYCLSYIAKI KLPKKRGTFI EFRNGMLNVS PIGRSCSQEE RIEFYELDKK ENIRQKFVAD LRKEFAGKGL TFSIGGQISF DVFPDGWDKR YCLRHVENDG YKTIYFFGDK TMPGGNDHEI FTDPRTMGYS VTAPEDTRRI CELLFSTRTR PLEQKLISEE DLAANDILDY KDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
SDS-PAGE : |
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Gene Name : | PMM2 phosphomannomutase 2 [ Homo sapiens (human) ] |
Official Symbol : | PMM2 |
Synonyms : | PMM2; phosphomannomutase 2; CDG1; CDG1a; CDGS; PMM 2; |
Gene ID : | 5373 |
mRNA Refseq : | NM_000303 |
Protein Refseq : | NP_000294 |
MIM : | 601785 |
UniProt ID : | O15305 |
◆ Recombinant Protein
Pmm2-4956M | Recombinant Mouse Pmm2 Protein, Myc/DDK-tagged | +Inquiry |
PMM2-795C | Recombinant Cynomolgus PMM2 Protein, His-tagged | +Inquiry |
PMM2-3484R | Recombinant Rhesus monkey PMM2 Protein, His-tagged | +Inquiry |
PMM2-2822H | Recombinant Human Phosphomannomutase 2, His-tagged | +Inquiry |
PMM2-10437Z | Recombinant Zebrafish PMM2 | +Inquiry |
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◆ Lysates
PMM2-3087HCL | Recombinant Human PMM2 293 Cell Lysate | +Inquiry |
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