Recombinant Human PMM2 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human PMM2 Protein, Myc/DDK-tagged, C13 and N15-labeled

PMM2 Related Products

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Cat.No. : PMM2-6090H
Product Overview : PMM2 MS Standard C13 and N15-labeled recombinant protein (NP_000294) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : The protein encoded by this gene catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, which is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. Mutations in this gene have been shown to cause defects in glycoprotein biosynthesis, which manifests as carbohydrate-deficient glycoprotein syndrome type I.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 27.9 kDa
AA Sequence : MAAPGPALCL FDVDGTLTAP RQKITKEMDD FLQKLRQKIK IGVVGGSDFE KVQEQLGNDV VEKYDYVFPE NGLVAYKDGK LLCRQNIQSH LGEALIQDLI NYCLSYIAKI KLPKKRGTFI EFRNGMLNVS PIGRSCSQEE RIEFYELDKK ENIRQKFVAD LRKEFAGKGL TFSIGGQISF DVFPDGWDKR YCLRHVENDG YKTIYFFGDK TMPGGNDHEI FTDPRTMGYS VTAPEDTRRI CELLFSTRTR PLEQKLISEE DLAANDILDY KDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : PMM2 phosphomannomutase 2 [ Homo sapiens (human) ]
Official Symbol : PMM2
Synonyms : PMM2; phosphomannomutase 2; CDG1; CDG1a; CDGS; PMM 2;
Gene ID : 5373
mRNA Refseq : NM_000303
Protein Refseq : NP_000294
MIM : 601785
UniProt ID : O15305

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