Recombinant Human SORD Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human SORD Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : SORD-5389H
Product Overview : SORD MS Standard C13 and N15-labeled recombinant protein (NP_003095) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications. The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 38.3 kDa
AA Sequence : MAAAAKPNNL SLVVHGPGDL RLENYPIPEP GPNEVLLRMH SVGICGSDVH YWEYGRIGNF IVKKPMVLGH EASGTVEKVG SSVKHLKPGD RVAIEPGAPR ENDEFCKMGR YNLSPSIFFC ATPPDDGNLC RFYKHNAAFC YKLPDNVTFE EGALIEPLSV GIHACRRGGV TLGHKVLVCG AGPIGMVTLL VAKAMGAAQV VVTDLSATRL SKAKEIGADL VLQISKESPQ EIARKVEGQL GCKPEVTIEC TGAEASIQAG IYATRSGGTL VLVGLGSEMT TVPLLHAAIR EVDIKGVFRY CNTWPVAISM LASKSVNVKP LVTHRFPLEK ALEAFETFKK GLGLKIMLKC DPSDQNPTRT RPLEQKLISE EDLAANDILD YKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : SORD sorbitol dehydrogenase [ Homo sapiens (human) ]
Official Symbol : SORD
Synonyms : SORD; sorbitol dehydrogenase; L-iditol 2-dehydrogenase; SORD1;
Gene ID : 6652
mRNA Refseq : NM_003104
Protein Refseq : NP_003095
MIM : 182500
UniProt ID : Q00796

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