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Recombinant Human SORD Protein, Myc/DDK-tagged, C13 and N15-labeled
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| Cat.No. : | SORD-5389H |
| Product Overview : | SORD MS Standard C13 and N15-labeled recombinant protein (NP_003095) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
| Description : | Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications. The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Myc/DDK |
| Molecular Mass : | 38.3 kDa |
| AA Sequence : | MAAAAKPNNL SLVVHGPGDL RLENYPIPEP GPNEVLLRMH SVGICGSDVH YWEYGRIGNF IVKKPMVLGH EASGTVEKVG SSVKHLKPGD RVAIEPGAPR ENDEFCKMGR YNLSPSIFFC ATPPDDGNLC RFYKHNAAFC YKLPDNVTFE EGALIEPLSV GIHACRRGGV TLGHKVLVCG AGPIGMVTLL VAKAMGAAQV VVTDLSATRL SKAKEIGADL VLQISKESPQ EIARKVEGQL GCKPEVTIEC TGAEASIQAG IYATRSGGTL VLVGLGSEMT TVPLLHAAIR EVDIKGVFRY CNTWPVAISM LASKSVNVKP LVTHRFPLEK ALEAFETFKK GLGLKIMLKC DPSDQNPTRT RPLEQKLISE EDLAANDILD YKDDDDKV |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : | 50 μg/mL as determined by BCA |
| Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
| SDS-PAGE : |
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| Gene Name : | SORD sorbitol dehydrogenase [ Homo sapiens (human) ] |
| Official Symbol : | SORD |
| Synonyms : | SORD; sorbitol dehydrogenase; L-iditol 2-dehydrogenase; SORD1; |
| Gene ID : | 6652 |
| mRNA Refseq : | NM_003104 |
| Protein Refseq : | NP_003095 |
| MIM : | 182500 |
| UniProt ID : | Q00796 |
◆ Recombinant Protein
| Sord-6046M | Recombinant Mouse Sord Protein, Myc/DDK-tagged | +Inquiry |
| SORD-15762M | Recombinant Mouse SORD Protein | +Inquiry |
| SORD-4408R | Recombinant Rhesus monkey SORD Protein, His-tagged | +Inquiry |
| SORD-5544C | Recombinant Chicken SORD | +Inquiry |
| SORD-29H | Recombinant Human SORD Protein | +Inquiry |
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◆ Lysates
| SORD-1569HCL | Recombinant Human SORD 293 Cell Lysate | +Inquiry |
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