Recombinant Human TNFSF9 Protein, His-tagged
Cat.No. : | TNFSF9-876H |
Product Overview : | Recombinant Human TNFSF9 fused with His tag at C-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
- Download
Description : | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction. |
Source : | E. coli |
Tag : | His |
Form : | Lyophilized from a 0.2 µM filtered solution of PBS, pH 7.4 |
Molecular Mass : | 20.6kD |
AA Sequence : | MREGPELSPDDPAGLLDLRQGMFAQ LVAQNVLLIDGPLSWYSDPGLAGVS LTGGLSYKEDTKELVVAKAGVYYVF FQLELRRVVAGEGSGSVSLALHLQP LRSAAGAAALALTVDLPPASSEARN SAFGFQGRLLHLSAGQRLGVHLHTE ARARHAWQLTQGATVLGLFRVTPEI PAGLPSPRSELEHHHHHH* |
Endotoxin : | Endotoxin level is <0.1 ng/µg of protein (<1EU/µg). |
Purity : | >95% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Gene Name : | TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 [ Homo sapiens ] |
Official Symbol : | TNFSF9 |
Synonyms : | TNFSF9; tumor necrosis factor (ligand) superfamily, member 9; tumor necrosis factor ligand superfamily member 9; 4 1BB L; homolog of mouse 4 1BB L; receptor 4 1BB ligand; 4-1BBL; 4-1BB ligand; receptor 4-1BB ligand; homolog of mouse 4-1BB-L; CD137L; 4-1BB-L; |
Gene ID : | 8744 |
mRNA Refseq : | NM_003811 |
Protein Refseq : | NP_003802 |
MIM : | 606182 |
UniProt ID : | P41273 |
Products Types
◆ Recombinant Protein | ||
TNFSF9-322H | Recombinant Active Human TNFSF9 Protein, His-tagged(C-ter) | +Inquiry |
TNFSF9-2224H | Recombinant Human TNFSF9 Protein, His (Fc)-Avi-tagged | +Inquiry |
TNFSF9-584H | Recombinant Human TNFSF9 Protein, Fc-tagged | +Inquiry |
TNFSF9-307H | Active Recombinant Human TNFSF9 Protein (Arg71-Glu254), C-His tagged, Animal-free, Carrier-free | +Inquiry |
TNFSF9-585M | Recombinant Mouse TNFSF9 Protein, Fc-tagged | +Inquiry |
◆ Lysates | ||
TNFSF9-1445RCL | Recombinant Rat TNFSF9 cell lysate | +Inquiry |
TNFSF9-2810MCL | Recombinant Mouse TNFSF9 cell lysate | +Inquiry |
TNFSF9-1444RCL | Recombinant Rat TNFSF9 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (0)
Ask a questionAsk a Question for All TNFSF9 Products
Required fields are marked with *
My Review for All TNFSF9 Products
Required fields are marked with *
0
Inquiry Basket