Recombinant Mouse Chemokine (C-X-C motif) ligand 1, His-tagged Cxcl1-377M

Recombinant Mouse Chemokine (C-X-C motif) ligand 1, His-tagged

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Cat.No. : Cxcl1-377M Optional Service: Optional requirements on this protein
Product Overview : Recombinant mouse Cxcl1protein, fused to His-tag at N-terminus, was expressed in E.coli and purifiedby using conventional chromatography techniques
Description : Cxcl1, also known asGROA or GRO-alpha, is a growth factor for melanoma cells and a chemotaxin forneutrophils. Similar to other alpha chemokines, this protein is potentneutrophil attractant and activator and is also active toward basophils. Inaddition, Cxcl1 protein may be a therapeutic target as well as a diagnosticmarker in ovarian cancer.
Source : E. coli
Species : Mouse
Form : Liquid. 20mMTris-HCl buffer (pH 8.0) containing 10% glycerol 0.1M NaCl.
Molecular Weight : 10.5 kDa(97aa), confirmedby MALDI-TOF.
Purity : > 90% by SDS -PAGE.
Concentration : 0.5mg/ml (determinedby Bradford assay).
Sequences of aminoacids : MGSSHHHHHHSSGLVPRGSH MGSHMAPIAN ELRCQCLQTM AGIHLKNIQS LKVLPSGPHC TQTEVIATLK NGREACLDPEAPLVQKIVQK MLKGVPK
Storage : Can be stored at+4°C short term (1-2 weeks). For long term storage, aliquot and store at-20°C or -70°C. Avoid repeated freezing and thawing cycles.
OfficialSymbol : Cxcl1
PDB rendering basedon 1mgs. :

Gene Name : Cxcl1 chemokine (C-X-C motif)ligand 1 [ Mus musculus ]
Synonyms : Cxcl1; chemokine(C-X-C motif) ligand 1; KC; Fsp; N51; gro; Gro1; Mgsa; Scyb1;growth-regulated alpha protein; KC/GR)-alpha; KC/GRO-alpha; GRO1 oncogene; secretoryprotein N51; C-X-C motif chemokine 1; platelet-derived growth; factor-inducibleprotein KC
Gene ID : 14825
mRNA Refseq : NM_008176
Protein Refseq : NP_032202
UniProt ID : P12850
Chromosome Location : 5 E-F; 5 51.0 cM
Pathway : Chemokine receptorsbind chemokines; Chemokine signaling pathway; Class A/1 (Rhodopsin-likereceptors); Cytokine-cytokine receptor interaction; Cytokines andInflammatory Response (BioCarta); G alpha (i) signalling events; GPCRdownstream signaling; GPCR ligand binding; Legionellosis; Legionellosis;NOD-like receptor signaling pathway; Peptide ligand-binding receptors;Salmonella infection; Signal Transduction; Signaling by GPCR
Function : chemokine activity;cytokine activity; growth factor activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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