Recombinant Mouse Chemokine (C-X-C motif) ligand 1, His-tagged

• Cat.No.: Cxcl1-377M
• Product Overview: Recombinant mouse Cxcl1protein, fused to His-tag at N-terminus, was expressed in E.coli and purifiedby using conventional chromatography techniques

Specification

• Species: Mouse
• Source: E.coli
• Tag: His
• Description: Cxcl1, also known asGROA or GRO-alpha, is a growth factor for melanoma cells and a chemotaxin forneutrophils. Similar to other alpha chemokines, this protein is potentneutrophil attractant and activator and is also active toward basophils. Inaddition, Cxcl1 protein may be a therapeutic target as well as a diagnosticmarker in ovarian cancer.
• Form: Liquid. 20mMTris-HCl buffer (pH 8.0) containing 10% glycerol 0.1M NaCl.
• Molecular Weight: 10.5 kDa(97aa), confirmedby MALDI-TOF.
• Purity: > 90% by SDS -PAGE.
• Concentration: 0.5mg/ml (determinedby Bradford assay).
• Sequences of aminoacids: MGSSHHHHHHSSGLVPRGSH MGSHMAPIAN ELRCQCLQTM AGIHLKNIQS LKVLPSGPHC TQTEVIATLK NGREACLDPEAPLVQKIVQK MLKGVPK
• Storage: Can be stored at+4°C short term (1-2 weeks). For long term storage, aliquot and store at-20°C or -70°C. Avoid repeated freezing and thawing cycles.
• OfficialSymbol: Cxcl1

Gene Information

• Gene Name: Cxcl1 chemokine (C-X-C motif)ligand 1 [ Mus musculus ]
• Synonyms: Cxcl1; chemokine(C-X-C motif) ligand 1; KC; Fsp; N51; gro; Gro1; Mgsa; Scyb1;growth-regulated alpha protein; KC/GR)-alpha; KC/GRO-alpha; GRO1 oncogene; secretoryprotein N51; C-X-C motif chemokine 1; platelet-derived growth; factor-inducibleprotein KC
• Gene ID: 14825
• mRNA Refseq: NM_008176
• Protein Refseq: NP_032202
• UniProt ID: P12850
• Chromosome Location: 5 E-F; 5 51.0 cM
• Pathway: Chemokine receptorsbind chemokines; Chemokine signaling pathway; Class A/1 (Rhodopsin-likereceptors); Cytokine-cytokine receptor interaction; Cytokines andInflammatory Response (BioCarta); G alpha (i) signalling events; GPCRdownstream signaling; GPCR ligand binding; Legionellosis; Legionellosis;NOD-like receptor signaling pathway; Peptide ligand-binding receptors;Salmonella infection; Signal Transduction; Signaling by GPCR
• Function: chemokine activity;cytokine activity; growth factor activity