Recombinant Mouse Timp1 protein, His-tagged


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Recombinant Mouse Timp1 protein, His-tagged

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Cat.No. : Timp1-69M
Product Overview : Recombinant Mouse TIMP1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Description : TIMP1, also known as metalloproteinase inhibitor 1, is a member of the TIMP family. Tissue inhibitors of metalloproteinases (TIMP) family are natural inhibitors of the matrix metalloproteinases (MMPs), the zinc enzymes involved in extracellular matrix maintenance and remodeling. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. It has been identified as a multifunctional molecule with divergent functions.
Source : Insect cell
Species : Mouse
Tag : His
Form : Liquid. In Phosphate Buffered Saline (pH 7.4), 10% glycerol
Molecular Mass : 21.0kDa (187aa)18-28kDa (SDS-PAGE under reducing conditions)
Endotoxin : < 1.0 EU per 1 microgram of protein (determined by LAL method)
Purity : >95% by SDS – PAGE
Storage : Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 0.5mg/ml (determined by Absorbance at 280nm)
Gene Name : Timp1 tissue inhibitor of metalloproteinase 1 [ Mus musculus ]
Official Symbol : Timp1
Synonyms : TIMP1; tissue inhibitor of metalloproteinase 1; metalloproteinase inhibitor 1; EPA; TPA-S1; TPA-induced protein; erythroid-potentiating activity; collagenase inhibitor 16C8 fibroblast; tissue inhibitor of metalloproteinase-1; tissue inhibitor of metalloproteinases 1; Clgi; Timp; TIMP-1; MGC7143;
Gene ID : 21857
mRNA Refseq : NM_001044384
Protein Refseq : NP_001037849
UniProt ID :
Pathway : Hemostasis, organism-specific biosystem; Matrix Metalloproteinases, organism-specific biosystem; Platelet activation, signaling and aggregation, organism-specific biosystem; Platelet degranulation, organism-specific biosystem; Response to elevated platelet cytosolic Ca2+, organism-specific biosystem;
Function : enzyme inhibitor activity; metal ion binding; metalloendopeptidase inhibitor activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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