Recombinant Rat Timp1 protein, His-tagged
Cat.No. : | Timp1-2790R |
Product Overview : | Recombinant Rat Timp1 aa. (Cys24~Ala217 (Accession # P30120)) fused with N-terminal His tag was produced in E. coli cells. |
- Specification
- Gene Information
- Related Products
Source : | E. coli |
Species : | Rat |
Tag : | His |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 23.1kDa |
Protein length : | Cys24~Ala217 (Accession # P30120) |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | >95% |
Characteristic : | The isoelectric point is 8. |
Applications : | SDS-PAGE; WB; ELISA; IP. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl. |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4. |
Gene Name : | Timp1 TIMP metallopeptidase inhibitor 1 [ Rattus norvegicus (Norway rat) ] |
Official Symbol : | Timp1 |
Synonyms : | Timp; TIMP-1; tissue inhibitor of metallopeptidase 1; tissue inhibitor of metalloproteinase 1; tissue inhibitor of metalloproteinases 1; metalloproteinase inhibitor 1 |
Gene ID : | 116510 |
mRNA Refseq : | NM_053819.1 |
Protein Refseq : | NP_446271.1 |
UniProt ID : | P30120 |
Products Types
◆ Recombinant Protein | ||
TIMP1-001H | Recombinant Human TIMP1 Protein, MBP-tagged | +Inquiry |
TIMP1-4491H | Recombinant Human TIMP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
TIMP1-0058H | Recombinant Human TIMP1 Protein | +Inquiry |
Timp1-01M | Recombinant Mouse Timp1 Protein, His-tagged | +Inquiry |
TIMP1-5733R | Recombinant Rat TIMP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
TIMP1-91B | Active Native Bovine Thrombin | +Inquiry |
TIMP1-92H | Native Human TIMP-1 | +Inquiry |
TIMP1-30840TH | Native Human TIMP1 | +Inquiry |
◆ Lysates | ||
TIMP1-1490RCL | Recombinant Rat TIMP1 cell lysate | +Inquiry |
TIMP1-2678HCL | Recombinant Human TIMP1 cell lysate | +Inquiry |
TIMP1-2376MCL | Recombinant Mouse TIMP1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionDysregulated TIMP1 expression in cancer can disrupt the balance between MMPs and TIMPs, contributing to excessive extracellular matrix degradation, invasion, and metastasis.
TIMP1 inhibits metalloproteinases by forming a complex with them, blocking their active sites and preventing the degradation of extracellular matrix components.
FXN's nuclear localization is associated with its involvement in DNA repair processes, influencing genomic stability and contributing to the overall cellular response to stress.
TIMP1 has immunomodulatory effects, influencing inflammation by regulating immune cell migration, cytokine production, and interactions with the extracellular matrix.
TIMP1 plays a crucial role in tissue homeostasis and repair by controlling the activity of MMPs, which are involved in remodeling the extracellular matrix during physiological and pathological processes.
Customer Reviews (3)
Write a reviewThe efficient delivery of this product ensured that our research timelines were met without any complications.
Impressed by the professionalism of the customer service team—responsive and knowledgeable about the entire product range.
This recombined protein has become a go-to in our lab due to its reliability and the precision it brings to our experiments.
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