Recombinant Mouse Tubg1 Protein, MYC/DDK-tagged
Cat.No. : | Tubg1-233M |
Product Overview : | Purified recombinant protein of full-length mouse tubulin, gamma 1 (Tubg1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation. |
Source : | HEK293T |
Species : | Mouse |
Tag : | MYC/DDK |
Molecular Mass : | 51.1 kDa |
Purity : | >80%, as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Tubg1 tubulin, gamma 1 [ Mus musculus (house mouse) ] |
Official Symbol : | Tubg1 |
Synonyms : | Tubg1; tubulin, gamma 1; Tubg; GCP-1; AI451582; AI503389; 1500010O08Rik; tubulin gamma-1 chain; gamma-tubulin complex component 1; tubulin, gamma polypeptide |
Gene ID : | 103733 |
mRNA Refseq : | NM_134024 |
Protein Refseq : | NP_598785 |
UniProt ID : | P83887 |
Products Types
◆ Recombinant Protein | ||
TUBG1-4840R | Recombinant Rhesus Macaque TUBG1 Protein, His (Fc)-Avi-tagged | +Inquiry |
TUBG1-2279H | Recombinant Human TUBG1 Protein, His (Fc)-Avi-tagged | +Inquiry |
TUBG1-12H | Recombinant Human TUBG1 Protein (1-451aa), C-6×His tagged | +Inquiry |
TUBG1-9765M | Recombinant Mouse TUBG1 Protein, His (Fc)-Avi-tagged | +Inquiry |
TUBG1-17624M | Recombinant Mouse TUBG1 Protein | +Inquiry |
◆ Lysates | ||
TUBG1-644HCL | Recombinant Human TUBG1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionThere are still some limitations in the current research on TUBG1, such as the lack of in-depth research on its specific mechanism of action and function, and the incomplete understanding of its relationship with diseases. In addition, since TUBG1 is an important component of the cytoskeleton, its regulation may also have some side effects.
Studies have shown that the expression level of TUBG1 is associated with some neurological diseases. For example, in the brains of patients with Alzheimer's disease (AD), the expression levels of TUBG1 are downregulated, which can lead to neuronal damage and death. In some tumors, the expression level of TUBG1 is upregulated, which may promote the proliferation and metastasis of tumor cells.
The expression level of TUBG1 can be detected by immunohistochemistry, western blotting, real-time PCR and other methods. These methods can detect protein or mRNA levels of TUBG1 in tissues or cells to assess changes in its expression in disease.
Recent studies have found that TUBG1 is also involved in cell cycle regulation and DNA repair processes. These processes have an important impact on the survival and death of cells, and also provide new ideas for the treatment of some diseases related to TUBG1.
Therapeutic strategies for TUBG1 include modulating its expression levels, inhibiting its activity, or using gene therapy. For example, some studies have shown that the use of microtubule stabilizers can increase the expression level and activity of TUBG1, thereby treating some TUBG1-related neurological diseases.
TUBG1 has complex relationships with other genes or proteins. For example, it interacts with other members of the tubulin family to form microtubules. In addition, TUBG1 is regulated by a number of transcription factors and signal transduction pathways.
Customer Reviews (3)
Write a reviewThe activity is strong, and the experimental effect is obvious.
Enzyme activity and receptor binding activity are very good.
The consistency is good, and the results of multiple experiments are highly reproducible.
Ask a Question for All Tubg1 Products
Required fields are marked with *
My Review for All Tubg1 Products
Required fields are marked with *
Inquiry Basket