Staurosporine, GMP Grade

• Cat.No.: Staurosporine-14
• Product Overview: Staurosporine (AM-2282) (GMP) is Staurosporine produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture.

Specification

• Description: Staurosporine is a potent, ATP-competitive and non-selective inhibitor of protein kinases.
• Form: Solid, Off-white to pale purple
• Target: PKC
• In Vitro: Staurosporine (GMP) (316 nM; 24 h) induces robust neurite outgrowth in RGC-5 cells. Staurosporine (GMP) (25 and 100 nM; 12 h) induces differentiation of SH-SY5Y cells, characterized by increased neurite outgrowth with significant branching and reduced cell body size. Staurosporine (GMP) (20 nM) induces differentiation of human neuroblastoma cell lines. Staurosporine (GMP) (5 nM) enhances differentiation of HL-60 cells induced by 1 alpha, 25 dihydroxyvitamin D3, dbc AMP, all-trans retinoic acid (RA), actinomycin D (Act D), and other compounds. Staurosporine (GMP) (1 μM; 15 d) induces differentiation of human neuroblastoma cells.
• CAS: 62996-74-1
• Formula: C28H26N4O3
• Molecular Mass: 466.53
• Storage: 4 centigrade, sealed storage, away from moisture and light

Gene Information

• Pathway: Epigenetics; TGF-beta/Smad
• Synonyms: Staurosporine; Antibiotic AM-2282; STS; AM-2282