b2m
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  • Official Full Name
  • beta-2-microglobulin
  • Background
  • This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.
  • Synonyms
  • B2M; beta-2-microglobulin; Beta-2-microglobulin; beta chain of MHC class I molecules; beta-2-microglobin
Cat.#:FCGRT & B2MTag:His|StrepII
Source (Host):HEK293Species:Human
Product nameRecombinant Human FCGRT & B2M Protein, His/Strep II-tagged, Biotinylated
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Cat.#:FCGRT & B2M-11BTag:His|Avi
Source (Host):HEK293Species:Bovine
Product nameRecombinant Bovine FCGRT & B2M Protein, His-Avi-tagged, Biotinylated
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Cat.#:FCGRT & B2M-12FTag:His|Avi
Source (Host):HEK293Species:Feline
Product nameRecombinant Feline FCGRT & B2M Protein, His-Avi-tagged, Biotinylated
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Cat.#:FCGRT & B2M-1928HTag:His|Avi|StrepII
Source (Host):HEK293Species:Human
Product nameRecombinant Human FCGRT & B2M Protein, His-Avi/Strep II-tagged, Biotinylated
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Cat.#:B2M-2208HTag:Myc|DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human B2M Protein, MYC/DDK-tagged
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Cat.#:B2M-002HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human B2M protein, GST-tagged
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Cat.#:B2M-10092HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human B2M, GST-tagged
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Cat.#:B2M-1656HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human B2M, His-tagged
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Cat.#:B2M-205HTag:DDK
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human B2M Protein, DDK-tagged
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Cat.#:B2M-206HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human B2M Protein
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Cat.#:B2M-218HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human B2M, C13&N15-labeled
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Cat.#:B2M-26758THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human B2M, His-tagged
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Cat.#:B2M-26790THTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human B2M
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Cat.#:B2M-315HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human B2M Protein, His-tagged
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Cat.#:B2M-3237HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human B2M, His tagged
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Cat.#:B2M-443HTag:His
Source (Host):HEK293FSpecies:Human
Product nameRecombinant Human B2M protein, His-tagged
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Cat.#:B2M-76HTag:His
Source (Host):YeastSpecies:Human
Product nameRecombinant Human B2M, His-tagged
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Cat.#:CD1B & B2M-249HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD1B & B2M protein, His-tagged
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Cat.#:CD1D & B2M-250HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD1D(Met1-Ser301)& B2M(Met1-Met119) protein, His-tagged
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Cat.#:B2m-316MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse B2m Protein, His-tagged
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Cat.#:B2M-938MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse B2M Protein, His-tagged
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Cat.#:B2M-1111RTag:His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat B2M Protein, His-tagged
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Cat.#:B2m-317RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat B2m Protein, His-tagged
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Cat.#:B2M-913RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat B2M Protein
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Cat.#:B2M-1200CTag:His
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus B2M Protein, His-tagged
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Cat.#:CD1E & B2M-197CTag:His
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus CD1E & B2M protein, His-tagged
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Cat.#:B2M-488RTag:His
Source (Host):HEK293Species:Rhesus macaque
Product nameRecombinant Rhesus macaque B2M Protein, His-tagged
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Cat.#:B2M-314DTag:His|GST
Source (Host):E. coliSpecies:Dog
Product nameRecombinant Dog TRIM21 Protein, His/GST-tagged
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Cat.#:B2M-1146CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken B2M
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Cat.#:B2M-7425ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish B2M
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Cat.#:B2M-81HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Beta-2-microglobulin
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Cat.#:B2M-1905HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human Beta-2-Microglobulin
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Cat.#:B2M-2722HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Beta-2-microglobulin, His-tagged
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Cat.#:B2M-13HTag:N/A
Source (Host):Species:Human
Product nameNative Human B2M
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Cat.#:B2M-5366HTag:N/A
Source (Host):Human urine from patients with tubular proteinuriaSpecies:Human
Product nameNative Human Beta-2-Microglobulin
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Cat.#:B2M-8046HTag:N/A
Source (Host):Human UrineSpecies:Human
Product nameNative Human Beta 2 MicroGlobulin
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Cat.#:B2M-2204HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human B2M cell lysate
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Cat.#:CD1B & B2M-001HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD1B & B2M cell lysate
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Cat.#:CD1D & B2M-001HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD1D & B2M cell lysate
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Cat.#:FCGRT & B2M-1925HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human FCGRT & B2M cell lysate
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Cat.#:B2M-1656MCLTag:N/A
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse B2M cell lysate
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Cat.#:FCGRT & B2M-1545MCLTag:N/A
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse FCGRT & B2M cell lysate
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Cat.#:B2M-1550RCLTag:N/A
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat B2M cell lysate
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Cat.#:FCGRT & B2M-1535RCLTag:N/A
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat FCGRT & B2M cell lysate
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Cat.#:B2M-1512CCLTag:N/A
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus B2M cell lysate
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Cat.#:CD1E & B2M-001CCLTag:N/A
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus CD1E & B2M cell lysate
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Cat.#:FCGRT & B2M-1534CCLTag:N/A
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus FCGRT & B2M cell lysate
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Cat.#:B2M-6HTag:N/A
Source (Host):Species:Human
Product nameHuman beta 2-Microglobulin Reference Standard
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Cat.#:B2m-72RTag:N/A
Source (Host):Species:Rat
Product nameRat beta 2-Microglobulin Reference Standard
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Involved Pathway

B2M involved in several pathways and played different roles in them. We selected most pathways B2M participated on our site, such as Antigen processing and presentation, which may be useful for your reference. Also, other proteins which involved in the same pathway with B2M were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Antigen processing and presentation
NFYC; HSPA1L; KIR3DL1; HLA-C; HLA-DRB4; HSPA6; CD74; TAP2; KLRC4; KIR2DS4

Protein Function

B2M has several biochemical functions, for example, glycoprotein binding, identical protein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by B2M itself. We selected most functions B2M had, and list some proteins which have the same functions with B2M. You can find most of the proteins on our site.
Function
Related Protein
Function glycoprotein binding
Related Protein FBXO2; BMPR1B; RAB14; OS9; EDEM1; SDC1; FBXO17; B2M; Serpina1c; TFR2
Function identical protein binding
Related Protein TPRG1L; TRAF2; IFIT3; CCDC109A; GOT2; HOMER1; BNIP3; HOOK3; MTSS1; HSPB1
Function protein binding
Related Protein NR1H2; CYTIP; ACOT7; MEAF6; RAB11FIP2; CD300LG; ROBO2; NUDC; FTSJ3; ARHGEF3

Interacting Protein

B2M has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with B2M here. Most of them are supplied by our site. Hope this information will be useful for your research of B2M.
HFE; CD1A; CD1B; HLA-A

B2M Related Articles

Oliveira, AC; de Sevilla, AF; et al. Prospective study of prognostic factors in asymptomatic patients with B-cell chronic lymphocytic leukemia-like lymphocytosis: the cut-off of 11 x 10(9)/L monoclonal lymphocytes better identifies subgroups with different outcomes. ANNALS OF HEMATOLOGY 94:627-632(2015).
Park, SJ; Kwon, SG; et al. Selection of appropriate reference genes for RT-qPCR analysis in Berkshire, Duroc, Landrace, and Yorkshire pigs. GENE 558:152-158(2015).