Human B2M Knockdown Cell Lysate

• Cat.No.: B2M-064HKCL
• Product Overview: WB-validated B2M Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 14 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg B2M KD HeLa cell lysate
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Antigen processing and presentation
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: B2M beta-2-microglobulin [ Homo sapiens (human) ]
• Official Symbol: B2M
• Synonyms: B2M; beta-2-microglobulin; beta-2-microglobin; beta chain of MHC class I molecules
• Gene ID: 567
• mRNA Refseq: NM_004048
• Protein Refseq: NP_004039
• MIM: 109700
• UniProt ID: P61769