birc7
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  • Official Full Name
  • baculoviral IAP repeat containing 7
  • Background
  • PUMA (p53 up-regulated modulator of apoptosis) is one of the pro-apoptotic Bcl-2 family members that are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-alpha and PUMA-beta. PUMA proteins bind Bcl-
  • Synonyms
  • BIRC7; baculoviral IAP repeat containing 7; baculoviral IAP repeat-containing protein 7; KIAP; kidney inhibitor of apoptosis protein; livin; livin inhibitor of apoptosis; melanoma inhibitor of apoptosis protein; ML IAP; mliap; RNF50; RING finger protein 5
Cat.#:BIRC7-229HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BIRC7, His-tagged
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Cat.#:BIRC7-231HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human BIRC7 Protein, GST-tagged
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Cat.#:BIRC7-232HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human BIRC7 Protein, GST-tagged
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Cat.#:BIRC7-432HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BIRC7, His-tagged
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Cat.#:BIRC7-636HTag:GST
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human BIRC7 Protein, GST-tagged, Active
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Cat.#:BIRC7-2411MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse BIRC7 Protein
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Cat.#:BIRC7-5722ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish BIRC7
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Cat.#:BIRC7-375HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Baculoviral IAP Repeat-containing 7, His-tagged
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Cat.#:BIRC7-8447HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human BIRC7 293 Cell Lysate
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Cat.#:BIRC7-8448HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human BIRC7 293 Cell Lysate
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Involved Pathway

BIRC7 involved in several pathways and played different roles in them. We selected most pathways BIRC7 participated on our site, such as Ubiquitin mediated proteolysis, Apoptosis, Toxoplasmosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with BIRC7 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Ubiquitin mediated proteolysis
ITCHA; HUWE1; ANAPC4; MGRN1B; PML; WWP2; UBE2G1A; CDC34; PIAS4A; UBE2G2
Apoptosis
TNFRSFA; DIABLOA; LMNB1; PPP3R1B; AKT2; PIK3CG; TNF; PPP3CA; NGF; TNFRSF10C
Toxoplasmosis
MAPK11; HLA-DOB; PIK3CD; MYD88; LAMB1; ITGB1; HSPA1L; TLR4; GNAI1; BIRC7
Pathways in cancer
CCNE1; WNT9A; Fgf15; VEGFC; DAPK2; AHA-1; FZD3; RALB; BMP4; APPL1
Small cell lung cancer
TRAF5; LAMB2; TRAF3; PTK2; PIK3CG; NFKBIA; CASP9; PTEN; AKT2; RXRG

Protein Function

BIRC7 has several biochemical functions, for example, cysteine-type endopeptidase inhibitor activity, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BIRC7 itself. We selected most functions BIRC7 had, and list some proteins which have the same functions with BIRC7. You can find most of the proteins on our site.
Function
Related Protein
Function cysteine-type endopeptidase inhibitor activity
Related Protein AHSG2; Cstb; CSTA; SERPINB13; CARD17; LCN1; CST3; NAIP1; BIRC5B; CSTL1
Function cysteine-type endopeptidase inhibitor activity involved in apoptotic process
Related Protein BIRC7; RPS6KA1; VIL1; PRDX5; SNCA; CD27; BIRC2; RPS6KA3; SERPINB9; AVP
Function enzyme binding
Related Protein SCNM1-PS; KRT79; PLSCR4; CD4; CYP3A4; CYP1A2; CRB2; NOXO1; KALRN; PRMT1
Function ligase activity
Related Protein LIG4; BARD1; RNF2; RNF169; DTX2; TRIM17; RAD18; UBE2G1B; RNF114; RNF146
Function protein binding
Related Protein BST2; RYR2; EPAS1; TFAM; ISY1; VPS28; CEP85; PAX3; EPCAM; TMX3
Function ubiquitin-protein transferase activity
Related Protein RNF187; SIAH1A; WWP2; FBXL6; TRIM5; RNF144AB; FBXW2; ITCHA; BIRC3; TRAF3
Function zinc ion binding
Related Protein XIAP; SIRT6; ZNF276; ZCCHC7; RNF112; GATA6; MKRN3; ZCCHC12; APOBEC3C; FHL1A

Interacting Protein

BIRC7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BIRC7 here. Most of them are supplied by our site. Hope this information will be useful for your research of BIRC7.
CASP9; DIABLO; POLR1C; PHF1

BIRC7 Related Articles

Durinck, S; Stawiski, EW; et al. Spectrum of diverse genomic alterations define non-clear cell renal carcinoma. NATURE GENETICS 47:13-+(2015).
Vital, DAL; de Mejia, EG; et al. Peptides in common bean fractions inhibit human colorectal cancer cells. FOOD CHEMISTRY 157:347-355(2014).