cd27
Share
  • Official Full Name
  • CD27 molecule
  • Background
  • The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]
  • Synonyms
  • CD27; CD27 molecule; T14; S152; Tp55; TNFRSF7; S152. LPFS2; CD27 antigen; CD27L receptor; T cell activation antigen S152; T-cell activation antigen CD27; tumor necrosis factor receptor superfamily, member 7;
Cat.#:CD27-1079HTag:HlgG1 Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD27 Protein (Met1-Ile192), HlgG1 Fc-tagged
+Inquiry
Cat.#:CD27-324HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human CD27 Protein (Met1-Ile192), His-tagged, Biotinylated
+Inquiry
Cat.#:CD27-335CTag:MIgG2a Fc
Source (Host):HEK293Species:Cynomolgus / Rhesus Monkey
Product nameRecombinant Cynomolgus / Rhesus Monkey CD27 Protein, MIgG2a Fc-tagged, low endotoxin
+Inquiry
Cat.#:CD27-336HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD27 Protein, His-tagged
+Inquiry
Cat.#:CD27-337HTag:MIgG2a Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD27 Protein, MIgG2a Fc-tagged, low endotoxin
+Inquiry
Cat.#:CD27-357MTag:MIgG2a Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse CD27 Protein, MIgG2a Fc-tagged, low endotoxin
+Inquiry
Cat.#:CD27-946RTag:HlgG1 Fc
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat CD27 Protein (Met1-Arg183), HlgG1 Fc-tagged
+Inquiry
Cat.#:CD27-947RTag:MlgG2a Fc
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat CD27 Protein (Met1-Cys181), MlgG2a Fc-tagged
+Inquiry
Cat.#:CD27-001HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human CD27, MIgG2a Fc-tagged
+Inquiry
Cat.#:CD27-003HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human CD27, HIgG1 Fc-tagged
+Inquiry
Cat.#:CD27-141HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human CD27, Fc-tagged
+Inquiry
Cat.#:CD27-180HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD27 Protein, Fc-tagged
+Inquiry
Cat.#:CD27-26925THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human CD27
+Inquiry
Cat.#:CD27-556HTag:Fc
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human CD27, His tagged
+Inquiry
Cat.#:CD27-564HTag:Fc
Source (Host):Human cellsSpecies:Human
Product nameRecombinant Human CD27, Fc-tagged, Biotinylated
+Inquiry
Cat.#:CD27-572HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CD27 protein, His-tagged
+Inquiry
Cat.#:CD27-57HTag:Fc/Avi
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD27 Protein, Fc & Avi-tagged, Biotinylated
+Inquiry
Cat.#:CD27-638HTag:FC/His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD27, Fc-His tagged
+Inquiry
Cat.#:CD27-887HTag:DDK/His
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human CD27 Protein, DDK/His-tagged
+Inquiry
Cat.#:CD27-888HTag:Fc/His
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human CD27 Protein, Fc/His-tagged
+Inquiry
Cat.#:Cd27-3273MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Cd27, His tagged
+Inquiry
Cat.#:Cd27-840MTag:His/Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Cd27 Protein, His & Fc-tagged
+Inquiry
Cat.#:Cd27-643RTag:Fc Chimera
Source (Host):NSO cellsSpecies:Rat
Product nameRecombinant Rat Cd27, Fc Chimera
+Inquiry
Cat.#:CD27-1654RTag:
Source (Host):HEK293Species:Rhesus monkey
Product nameRecombinant Rhesus Monkey CD27 Protein
+Inquiry
Cat.#:CD27-493RTag:Fc
Source (Host):HEK293Species:Rhesus Macaque
Product nameRecombinant Rhesus CD27 protein, Fc-tagged
+Inquiry
Cat.#:CD27-1592HTag:FC/His
Source (Host):NS0Species:Human
Product nameRecombinant Human CD27 Molecule, Fc-His
+Inquiry
Cat.#:CD27-56HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD27 Molecule, Fc-Tagged
+Inquiry
Cat.#:CD27-7139HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CD27 Molecule, His-tagged
+Inquiry
Cat.#:Cd27-3258MTag:Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse CD27 Antigen, Fc Chimera
+Inquiry
Cat.#:CD27-001HCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human CD27 cell lysate
+Inquiry
Cat.#:CD27-1383HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD27 cell lysate
+Inquiry
Cat.#:CD27-2415MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse CD27 cell lysate
+Inquiry
Cat.#:CD27-1156CCLTag:
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus CD27 cell lysate
+Inquiry

Involved Pathway

Cd27 involved in several pathways and played different roles in them. We selected most pathways Cd27 participated on our site, such as Cytokine-cytokine receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with Cd27 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine-cytokine receptor interaction
TNFRSF21; CCR10; CTF1; IL15; FLT3; KITA; IL5RA; Flt3l; LEPA; ACVR2A

Protein Function

Cd27 has several biochemical functions, for example, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, protein binding, transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Cd27 itself. We selected most functions Cd27 had, and list some proteins which have the same functions with Cd27. You can find most of the proteins on our site.
Function
Related Protein
Function cysteine-type endopeptidase inhibitor activity involved in apoptotic process
Related Protein CD27; VIL1; GAS6; IGF1RA; BIRC2; SNCA; RPS6KA1; BIRC8; PRDX5; SERPINB9
Function protein binding
Related Protein PPP1R37; SULT2A1; TEAD4; ADAM8; KLK8; MYH7B; KHDRBS1; AAAS; SH2D1B; ARF4
Function transmembrane signaling receptor activity
Related Protein CALCRLA; CD69; CD5; OR4D6; TLR18; MARCO; DNER; SEMA4D; CELSR3; FZD9B
Function tumor necrosis factor-activated receptor activity
Related Protein TNFRSF21; TNFRSF10D; TNFRSF10B; TNFRSF11B; TNFRSF9; TNFRSF1B; TNFRSF8; TNFRSF9A; TNFRSF10C; TNFRSF4

Interacting Protein

Cd27 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Cd27 here. Most of them are supplied by our site. Hope this information will be useful for your research of Cd27.
SIVA1; UHRF2; TRAF2

Cd27 Related Articles

Convers, KD; Kariuki, BM; et al. Decreased CD5(-)CD19(+)CD27(+)CD43(+)CD70(-) B-Cell Subpopulation in Children with Specific Antibody Deficiency. PEDIATRIC ALLERGY IMMUNOLOGY AND PULMONOLOGY 28:27-31(2015).
Becerra, E; Scully, MA; et al. Effect of rituximab on B cell phenotype and serum B cell-activating factor levels in patients with thrombotic thrombocytopenic purpura. CLINICAL AND EXPERIMENTAL IMMUNOLOGY 179:414-425(2015).

Cd27 Related Gene Family

TNF Cytokines