Recombinant Human CD27 protein, His-tagged
Cat.No. : | CD27-6271H |
Product Overview : | Recombinant Human CD27 (Gln39-Pro193) protein was fused to His-tag at N-terminus and expressed in human 293 cells (HEK293). |
- Specification
- Gene Information
- Related Products
Description : | Cluster of Differentiation 70 (CD70) is also known as CD27 ligand (CD27L/CD27LG), TNFSF7, TNFSF7G, is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and is a surface antigen found on activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its receptor CD27 induces in priming, effector functions, differentiation and memory formation of T-cells, and thus is invloved in the biological processes including T-cell activation, the proliferation of costimulated T-cells, as well as the generation of cytolytic T-cells. CD70 on T cells provides costimulatory signals that are required for T cell proliferation, clonal expansion and the promotion of effector T cell formation. CD70 on mouse B cell has been shown to inhibit terminal differentiation of activated B cells into plasma cells and enhances commitment to memory B cell responses. CD70 induces proliferation and IFNγ production, on NK cells. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Predicted N Terminal : | Gln39 |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 19.0 kDa. The protein migrates as 30-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | Gln39-Pro193 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >90% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | CD27 |
Official Symbol : | CD27 |
Synonyms : | CD27; CD27 molecule; TNFRSF7, tumor necrosis factor receptor superfamily, member 7; CD27 antigen; S152; Tp55; CD27L receptor; T cell activation antigen S152; T-cell activation antigen CD27; tumor necrosis factor receptor superfamily, member 7; T14; TNFRSF7; MGC20393 |
Gene ID : | 939 |
mRNA Refseq : | NM_001242 |
Protein Refseq : | NP_001233 |
MIM : | 186711 |
UniProt ID : | P26842 |
Products Types
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Cd27-3273M | Active Recombinant Mouse Cd27 protein(Met1-Arg182), His-tagged | +Inquiry |
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CD27-223H | Recombinant Human CD27 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CD27-1156CCL | Recombinant Cynomolgus CD27 cell lysate | +Inquiry |
CD27-1383HCL | Recombinant Human CD27 cell lysate | +Inquiry |
CD27-2415MCL | Recombinant Mouse CD27 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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