klk1
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  • Official Full Name
  • kallikrein 1
  • Background
  • Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen. [provided by RefSeq, Jul 2008]
  • Synonyms
  • KLK1; kallikrein 1; hK1; KLKR; Klk6; kallikrein-1; tissue kallikrein; glandular kallikrein 1; kallikrein serine protease 1; kallikrein 1, renal/pancreas/salivary; kidney/pancreas/salivary gland kallikrein
Cat.#:KLK1-605HTag:GST/His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human KLK1 Protein, GST/His-tagged
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Cat.#:KLK1-29686THTag:
Source (Host):YeastSpecies:Human
Product nameRecombinant Human KLK1
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Cat.#:KLK1-299HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human KLK1, His tagged
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Cat.#:KLK1-38HTag:N/A
Source (Host):YeastSpecies:Human
Product nameRecombinant Human Kallikrein 1
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Cat.#:KLK1-643HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human KLK1, His-tagged
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Cat.#:KLK1-7198HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Kallikrein 1, His-tagged
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Cat.#:KLK1-727HTag:GST/His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human KLK1 Protein, GST-His-tagged
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Cat.#:KLK1-742HTag:His
Source (Host):NSO cellsSpecies:Human
Product nameRecombinant Human KLK1, His-tagged
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Cat.#:Klk1-519MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Klk1, His-tagged
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Cat.#:Klk1-5678MTag:His/GST
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Klk1 protein, His & GST-tagged
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Cat.#:KLK1-3288RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat KLK1 Protein
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Cat.#:Klk1-5679RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Klk1 protein, His-tagged
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Cat.#:KLK1-643CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus KLK1 Protein, His-tagged
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Cat.#:KLK1-29685THTag:
Source (Host):Species:Human
Product nameNative Human KLK1
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Cat.#:KLK1-2901HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human KLK1 cell lysate
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Cat.#:KLK1-743MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse KLK1 cell lysate
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Involved Pathway

KLK1 involved in several pathways and played different roles in them. We selected most pathways KLK1 participated on our site, such as Renin-angiotensin system, Endocrine and other factor-regulated calcium reabsorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with KLK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Renin-angiotensin system
ENPEP; Ren1; KLK1B26; ATP6AP2; KLK1B24; KLK2; KLK1B9; KLK1B5; REN2; REN
Endocrine and other factor-regulated calcium reabsorption
DNM2; SLC8A1; GNAQ; KLK1B5; KLK1; PRKCB; ATP1A2; DNM3; ATP1A1; KLK1B26

Protein Function

KLK1 has several biochemical functions, for example, serine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KLK1 itself. We selected most functions KLK1 had, and list some proteins which have the same functions with KLK1. You can find most of the proteins on our site.
Function
Related Protein
Function serine-type endopeptidase activity
Related Protein C1RA; KLK5; HABP2; PRSS46; OVCH2; FAP; PRSS22; MMP8; MASP2; KLK1B3

KLK1 Related Articles

El Annan, J; Jiang, GM; et al. Elevated Immunoglobulin to Tissue KLK11 in Patients With Sjogren Syndrome. CORNEA 32:E90-E93(2013).
Yamamuro, T; Hori, M; et al. Tickling stimulation causes the up-regulation of the kallikrein family in the submandibular gland of the rat. BEHAVIOURAL BRAIN RESEARCH 236:236-243(2013).