|Official Full Name||kallikrein 1|
|Background||Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen. [provided by RefSeq, Jul 2008]|
|Synonyms||KLK1; kallikrein 1; hK1; KLKR; Klk6; kallikrein-1; tissue kallikrein; glandular kallikrein 1; kallikrein serine protease 1; kallikrein 1, renal/pancreas/salivary; kidney/pancreas/salivary gland kallikrein|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
KLK1 involved in several pathways and played different roles in them. We selected most pathways KLK1 participated on our site, such as Renin-angiotensin system, Endocrine and other factor-regulated calcium reabsorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with KLK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Renin-angiotensin system||Ren1; REN2; CTSA; REN; MME; AGTR1B; LNPEP; ATP6AP2; ENPEP; MAS1|
|Endocrine and other factor-regulated calcium reabsorption||ATP1B3; KLK1B1; GNAS; KLK1B8; CALB1; KLK1B22; PRKACB; ATP1A4; KLK1B3; KLK1B11|
KLK1 has several biochemical functions, for example, serine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KLK1 itself. We selected most functions KLK1 had, and list some proteins which have the same functions with KLK1. You can find most of the proteins on our site.
|serine-type endopeptidase activity||HTRA1B; EGFBP2; PROCA; CORIN; ST14B; RHBDD2; TMPRSS4A; C1R; DPP4; MBTPS1|
KLK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KLK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of KLK1.