KLK1 Protein, kallikrein 1

KLK1

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KLK1

Official Full Name kallikrein 1
Background Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen. [provided by RefSeq, Jul 2008]
Synonyms KLK1; kallikrein 1; hK1; KLKR; Klk6; kallikrein-1; tissue kallikrein; glandular kallikrein 1; kallikrein serine protease 1; kallikrein 1, renal/pancreas/salivary; kidney/pancreas/salivary gland kallikrein
    • Species :
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • Human Cell
    • Mammalian Cell
    • Mouse
    • NS0
    • P.pastoris
    • Rabbit
    • Yeast
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CAB11569MH Mouse Anti-Human Kallikrein 1 Monoclonal Antibody Mouse N/A
    Human CAB11570RH Rabbit Anti-Human Kallikrein 1 Monoclonal Antibody Rabbit N/A
    Human KLK1-2901HCL Recombinant Human KLK1 cell lysate Human Cell N/A
    Human KLK1-29685TH Native Human KLK1 N/A
    Human KLK1-29686TH Recombinant Human KLK1 Yeast N/A
    Human KLK1-299H Recombinant Human KLK1, His tagged Human Cell His
    Human KLK1-38H Recombinant Human Kallikrein 1 P.pastoris N/A
    Human KLK1-605H Recombinant Human KLK1 Protein, GST/His-tagged E.coli GST/His
    Human KLK1-643H Recombinant Human KLK1, His-tagged E.coli His
    Human KLK1-7198H Recombinant Human Kallikrein 1, His-tagged E.coli His
    Human KLK1-727H Recombinant Human KLK1 Protein, GST-His-tagged E.coli GST/His
    Human KLK1-742H Recombinant Human KLK1, His-tagged NS0 His
    Mouse Klk1-519M Recombinant Mouse Klk1, His-tagged Human Cell His
    Mouse Klk1-5678M Recombinant Mouse Klk1 protein, His & GST-tagged E.coli His/GST
    Mouse KLK1-743MCL Recombinant Mouse KLK1 cell lysate Human Cell N/A
    Rat KLK1-3288R Recombinant Rat KLK1 Protein Mammalian Cell His
    Rat Klk1-5679R Recombinant Rat Klk1 protein, His-tagged E.coli His
    Cynomolgus Monkey KLK1-643C Recombinant Cynomolgus KLK1 Protein, His-tagged Mammalian Cell His

    KLK1 involved in several pathways and played different roles in them. We selected most pathways KLK1 participated on our site, such as Renin-angiotensin system, Endocrine and other factor-regulated calcium reabsorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with KLK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Renin-angiotensin system Ren1; REN2; CTSA; REN; MME; AGTR1B; LNPEP; ATP6AP2; ENPEP; MAS1
    Endocrine and other factor-regulated calcium reabsorption ATP1B3; KLK1B1; GNAS; KLK1B8; CALB1; KLK1B22; PRKACB; ATP1A4; KLK1B3; KLK1B11

    KLK1 has several biochemical functions, for example, serine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KLK1 itself. We selected most functions KLK1 had, and list some proteins which have the same functions with KLK1. You can find most of the proteins on our site.

    Function Related Protein
    serine-type endopeptidase activity HTRA1B; EGFBP2; PROCA; CORIN; ST14B; RHBDD2; TMPRSS4A; C1R; DPP4; MBTPS1

    KLK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KLK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of KLK1.

    El Annan, J; Jiang, GM; et al. Elevated Immunoglobulin to Tissue KLK11 in Patients With Sjogren Syndrome. CORNEA 32:E90-E93(2013).
    Yamamuro, T; Hori, M; et al. Tickling stimulation causes the up-regulation of the kallikrein family in the submandibular gland of the rat. BEHAVIOURAL BRAIN RESEARCH 236:236-243(2013).

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