Active Recombinant Mouse Klk1 protein(Met1-Asp261), His-tagged

• Cat.No.: Klk1-519M
• Product Overview: Recombinant Mouse Klk1 protein(P15947)(Met1-Asp261), fused with C-terminal His tag, was expressed in HEK293.

Specification

• similar: Klk1
• Alias: KLK1; kallikrein 1; kallikrein-1; KAL-B; kallikrein 6; renal kallikrein; tissue kallikrein-6; true tissue kallikrein; glandular kallikrein K1; kallikrein renal/pancreas/salivary; Kal; Klk6; mGk-6; Klk1b6; 0610007D04Rik
• Source: HEK293
• Species: Mouse
• Conjugate: C-His
• Tag: His
• Protein length: Met1-Asp261
• Form: Lyophilized from sterile 25 mM Tris, 5 mM CaCl2, 0.15 M NaCl, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
• MolecularMass: The recombinant mouse KLK1 comprises 254 amino acids and has a predicted molecular mass of 28.3 kDa. The apparent molecular mass of the protein is approximately 36 kDa in SDS-PAGE under reducing conditions.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: > 90 % as determined by SDS-PAGE
• Storage: Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
• GeneName: Klk1 kallikrein 1 [ Mus musculus ]
• GeneNameWeblink: 16612
• OfficialSymbol: Klk1
• OfficialSymbolWeblink: 16612
• GeneIDWeblink: 16612
• mRNARefseq: NM_010639
• mRNARefseqWeblink: NM_010639.7
• ProteinRefseqWeblink: NP_034769.4
• Synonyms: KLK1; kallikrein 1; kallikrein-1; KAL-B; kallikrein 6; renal kallikrein; tissue kallikrein-6; true tissue kallikrein; glandular kallikrein K1; kallikrein renal/pancreas/salivary; Kal; Klk6; mGk-6; Klk1b6; 0610007D04Rik
• Gene ID: 16612

Gene Information

• Synonyms: KLK1; kallikrein 1; kallikrein-1; KAL-B; kallikrein 6; renal kallikrein; tissue kallikrein-6; true tissue kallikrein; glandular kallikrein K1; kallikrein renal/pancreas/salivary; Kal; Klk6; mGk-6; Klk1b6; 0610007D04Rik
• Gene ID: 16612

Reviews

04/24/2019

Whether measuring analyte concentrations, screening for specific interactions, or monitoring immune responses, this protein's exceptional performance in ELISA experiments is truly commendable.

06/30/2018

Its high quality, reliability, and exceptional performance make it an excellent choice for a wide range of experimental applications.

12/12/2017

This strong track record of excellence further attests to the KLK1 protein's capability to meet the rigorous demands of research projects.

Q&As

How is KLK1 involved in coagulation and fibrinolysis?

KLK1 participates in the regulation of blood clotting and fibrinolysis by influencing the activation of certain coagulation factors and promoting fibrinolysis.

How does KLK1 impact renal function?

KLK1 contributes to renal function by promoting vasodilation in the renal blood vessels and influencing sodium and water excretion, which can be beneficial in kidney diseases.

Is KLK1 associated with cancer?

Some studies suggest that KLK1 may be involved in cancer progression, but the relationship is complex and not fully understood. Further research is needed.

Are there any clinical applications of KLK1 in inflammatory conditions?

Some studies suggest that KLK1-based therapies may have potential in managing inflammatory conditions, but more research is needed for conclusive evidence.

Are there any KLK1-based therapies for cancer?

The potential use of KLK1 in cancer therapy is an area of investigation, but no specific KLK1-based cancer therapies have been established yet.