ppbp
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  • Official Full Name
  • pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
  • Background
  • CXCL7 which is a protein with a length of 70 amino acids, belongs to the family of chemotactic cytokines. The expression of CXCL7 is induced in human monocytes by treatment with bacterial endotoxins. It stimulates the release of elastase from neutrophils and shows some of the activities of IL8. CXCL7 interacts with the NAP-1 receptor and binds to one type of receptors that also binds IL8 and related factors.
  • Synonyms
  • Ppbp; PPBP; pro-platelet basic protein (chemokine (C-X-C motif) ligand 7); platelet basic protein; neutrophil activating peptide-2; chemokine (C-X-C motif) ligand 7; Cxcl7; Nap-2
Cat.#:PPBP-2601HTag:Myc|DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human PPBP Protein, MYC/DDK-tagged
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Cat.#:PPBP-339HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Pro-Platelet Basic Protein (chemokine (C-X-C motif) ligand 7)
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Cat.#:Ppbp-392MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Pro-Platelet Basic Protein
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Cat.#:Ppbp-394MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Pro-Platelet Basic Protein
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Cat.#:Ppbp-448RTag:N/A
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Pro-Platelet Basic Protein (chemokine (C-X-C motif) ligand 7)
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Cat.#:PPBP-04H PPBPTag:N/A
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human PPBP protein
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Cat.#:PPBP-049HTag:N/A
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human PPBP Protein
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Cat.#:PPBP-04HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human chemokine (C-X-C Motif) Ligand 7
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Cat.#:PPBP-111HTag:N/A
Source (Host):Species:Human
Product nameHuman PPBP
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Cat.#:PPBP-1875HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PPBP, GST-tagged
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Cat.#:PPBP-206HTag:GST
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human PPBP, GST-tagged
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Cat.#:PPBP-29720THTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human PPBP
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Cat.#:PPBP-345HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PPBP, His-tagged
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Cat.#:PPBP-517HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PPBP Protein, His-tagged
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Cat.#:Ppbp-287MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Ppbp
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Cat.#:Ppbp-518MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Ppbp Protein, His-tagged
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Cat.#:Ppbp-845MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Ppbp Protein, His-tagged
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Cat.#:Ppbp-846MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Ppbp Protein, His-tagged
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Cat.#:PPBP-1073RTag:Fc
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat PPBP Protein, Fc-tagged
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Cat.#:Ppbp-520RTag:His|GST
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Ppbp Protein, His/GST-tagged
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Cat.#:Ppbp-521RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Ppbp Protein, His-tagged
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Cat.#:Ppbp-630RTag:N/A
Source (Host):E.coliSpecies:Rat
Product nameRecombinant Rat Ppbp protein
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Cat.#:PPBP-1195CTag:Fc
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus PPBP Protein, Fc-tagged
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Cat.#:PPBP-519PTag:His|GST
Source (Host):E. coliSpecies:Pig
Product nameRecombinant Pig PPBP Protein, His/GST-tagged
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Cat.#:PPBP-30279THTag:N/A
Source (Host):Species:Human
Product nameNative Human PPBP
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Cat.#:PPBP-1616RCLTag:N/A
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat PPBP cell lysate
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Cat.#:PPBP-1397CCLTag:N/A
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus PPBP cell lysate
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Cat.#:PPBP-70HTag:N/A
Source (Host):Species:Human
Product nameHuman Beta Thromboglobulin Reference standard
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Involved Pathway

PPBP involved in several pathways and played different roles in them. We selected most pathways PPBP participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPBP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine-cytokine receptor interaction
CCL16; IFNA17; IFNE; CCL24; IL13; CXCL2; KITLGB; IL5RA; ACVR2B; CSF1R
Chemokine signaling pathway
ROCK2; XCL2; PIK3R1; RAC1; AKT1; GNG2; CXCL11; GNAI1; GM10591; CCR7

Protein Function

PPBP has several biochemical functions, for example, CXCR chemokine receptor binding, chemokine activity, glucose transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPBP itself. We selected most functions PPBP had, and list some proteins which have the same functions with PPBP. You can find most of the proteins on our site.
Function
Related Protein
Function CXCR chemokine receptor binding
Related Protein CXCL1; IL8L2; ITCH; PF4V1; CXCL5; PPBP; CXCL12A; CXCL20; CXCL18B; CXCL2
Function chemokine activity
Related Protein CCL20B; CCL14; C5; CCL22; CXL34B.11; PF4V1; CCL3L1; CCL2; CCL13; CXCL16
Function glucose transmembrane transporter activity
Related Protein SLC2A5; SLC2A2; SLC2A9L1; SLC2A15A; SLC2A11B; SLC2A11L; SLC2A3A; PPBP; SLC2A8; SLC2A1A
Function growth factor activity
Related Protein BMP1; FGF10A; NRTN; LFT1; IGF2; CSF2; CSF1A; GDF6B; GDF10; INHBC

Interacting Protein

PPBP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPBP here. Most of them are supplied by our site. Hope this information will be useful for your research of PPBP.
EFNA1; NR4A1; RPS27; DMWD; PMAIP1; COX17; MAPK6; MOB3B; rarD; SCFD1; fadE; CELF1; QRSL1; STRN4; PLEKHJ1; NDUFB11; CMTM6; COPS7A; COPG1