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PPBP

  • Official Full Name

    pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)

  • Overview

    CXCL7 which is a protein with a length of 70 amino acids, belongs to the family of chemotactic cytokines. The expression of CXCL7 is induced in human monocytes by treatment with bacterial endotoxins. It stimulates the release of elastase from neutrophils and shows some of the activities of IL8. CXCL7 interacts with the NAP-1 receptor and binds to one type of receptors that also binds IL8 and related factors.
  • Synonyms

    Ppbp; PPBP; pro-platelet basic protein (chemokine (C-X-C motif) ligand 7); platelet basic protein; neutrophil activating peptide-2; chemokine (C-X-C motif) ligand 7; Cxcl7; Nap-2;

  • Recombinant Proteins
  • Transfected Stable Cell Lines
  • Native Proteins
  • Cell & Tissue Lysates
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Pig
  • Rabbit
  • Rat
  • CHO
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • Human
  • Human Cell
  • Human Cells
  • In Vitro Cell Free System
  • Mammalian cells
  • Wheat Germ
  • Biotin
  • C
  • His
  • Fc
  • GST
  • His|GST
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
  • Tag Free
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PPBP-111H Active Human PPBP N/A
Human PPBP-04H Recombinant Human chemokine (C-X-C Motif) Ligand 7 E.coli N/A
Human PPBP-29720TH Recombinant Human PPBP N/A
Human PPBP-339H Recombinant Human Pro-Platelet Basic Protein (chemokine (C-X-C motif) ligand 7) Human N/A
Human PPBP-1875H Recombinant Human PPBP, GST-tagged E.coli GST 31-128aa
Human PPBP-049H Recombinant Human PPBP Protein HEK293 N/A
Human PPBP-206H Recombinant Human PPBP, GST-tagged Wheat Germ GST
Human PPBP-517H Recombinant Human PPBP Protein, His-tagged E.coli His Ala59~Asp128
Human PPBP-345H Recombinant Human PPBP protein, His-tagged E.coli His Ala59-Asp128
Human PPBP-70H Human Beta Thromboglobulin Reference standard N/A
Human PPBP-2601H Recombinant Human PPBP Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human PPBP-04H PPBP Recombinant Human PPBP protein E.coli N/A 70
Human PPBP-227H Recombinant Human PPBP Protein E.coli
Human PPBP-30279TH Native Human PPBP N/A
Human PPBP-33H Recombinant Human PPBP Protein, Biotin-tagged E.coli Biotin
Human PPBP-3084H Recombinant Human PPBP Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PPBP-385HF Recombinant Full Length Human PPBP Protein, GST-tagged In Vitro Cell Free System GST 128 amino acids
Human PPBP-3363H Recombinant Human PPBP protein, GST-tagged E.coli GST 59-125aa
Human PPBP-215P Active Recombinant Human PPBP Protein (70 aa) CHO 70
Human PPBP-151H Recombinant Human PPBP Protein, His-tagged Human Cells His
Human PPBP-2149H Recombinant Human PPBP Protein (Ala59-Asp128) E.coli Tag Free Ala59-Asp128
Human PPBP-25H Recombinant Human PPBP Protein E.coli 70 amino acid
Human PPBP-251H Active Recombinant Human PPBP Protein (Ala59-Asp128), N-His tagged, Animal-free, Carrier-free E.coli N-His Ala59-Asp128
Human PPBP-068P Active Recombinant Human PPBP Protein (70 aa) E.coli 70
Human PPBP-2150H Recombinant Human PPBP Protein (Ser35-Asp128), C-His tagged Mammalian cells C-His Ser35-Asp128
Human PPBP-5943H Recombinant Human PPBP Protein (Ala59-Asp128), His tagged E.coli His Ala59-Asp128
Mouse Ppbp-287M Active Recombinant Mouse Ppbp E.coli N/A
Mouse Ppbp-392M Active Recombinant Mouse Pro-Platelet Basic Protein E.coli N/A
Mouse Ppbp-394M Active Recombinant Mouse Pro-Platelet Basic Protein E.coli N/A
Mouse Ppbp-518M Recombinant Mouse Ppbp Protein, His-tagged E.coli His Lys40~Tyr113
Mouse Ppbp-845M Recombinant Mouse Ppbp Protein, His-tagged E.coli His
Mouse Ppbp-846M Recombinant Mouse Ppbp Protein, His-tagged E.coli His
Mouse Ppbp-259M Active Recombinant Mouse Ppbp Protein (Lys40-Tyr113), N-His tagged, Animal-free, Carrier-free E.coli N-His Lys40-Tyr113
Mouse Ppbp-260M Active Recombinant Mouse Ppbp Protein (Ile48-Ile109), N-His tagged, Animal-free, Carrier-free E.coli N-His Ile48-Ile109
Mouse Ppbp-5457M Recombinant Mouse Ppbp Protein (Ile48-Ile109), N-His tagged E.coli N-His Ile48-Ile109
Mouse Ppbp-2162M Recombinant Mouse Ppbp protein, His-tagged E.coli His Lys40-Tyr113
Mouse Ppbp-5032M Active Recombinant Mouse Ppbp Protein E. coli Ile48-Ile109
Rat Ppbp-448R Active Recombinant Rat Pro-Platelet Basic Protein (chemokine (C-X-C motif) ligand 7) E.coli N/A
Rat PPBP-1073R Recombinant Rat PPBP Protein, Fc-tagged HEK293 Fc
Rat Ppbp-630R Recombinant Rat Ppbp protein E.coli N/A 62
Rat Ppbp-520R Recombinant Rat Ppbp Protein, His/GST-tagged E.coli His/GST Ile46~Ile107
Rat Ppbp-521R Recombinant Rat Ppbp Protein, His-tagged E.coli His Ile46~Ile107
Rat PPBP-1616RCL Recombinant Rat PPBP cell lysate Human Cell N/A
Rat Ppbp-204P Active Recombinant Rat Ppbp Protein (62 aa) CHO 62
Rat Ppbp-325P Active Recombinant Rat Ppbp Protein (62 aa) E.coli 62
Rabbit PPBP-1963R Recombinant Rabbit PPBP Protein, His-tagged E.coli N-His Gln40-Pro110
Cynomolgus Monkey PPBP-1195C Recombinant Cynomolgus PPBP Protein, Fc-tagged HEK293 Fc
Cynomolgus Monkey PPBP-1397CCL Recombinant Cynomolgus PPBP cell lysate Human Cell N/A
Pig PPBP-519P Recombinant Pig PPBP Protein, His/GST-tagged E.coli His/GST Met1~Ala119
  • Involved Pathway
  • Protein Function
  • Interacting Protein

PPBP involved in several pathways and played different roles in them. We selected most pathways PPBP participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPBP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine-cytokine receptor interactionCXCR4A;MPL;CCL25B;IL12RB2;CXCR1;IFNGR1;CCL21;INHBA;CCL13
Chemokine signaling pathwayCCL24;CXCL11;CCL26;ELMO1;CXCL14;CXCR2;JAK2;XCL2;SOS1

PPBP has several biochemical functions, for example, CXCR chemokine receptor binding, chemokine activity, glucose transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPBP itself. We selected most functions PPBP had, and list some proteins which have the same functions with PPBP. You can find most of the proteins on our site.

Function Related Protein
CXCR chemokine receptor bindingCXCL18B;PF4V1;CXCL3;CXCL6;CXCL12A;PPBP;CXCL1;CXCL5;ITCH
chemokine activityCCL13;CXCL11;IL-8;CCL34A.4;CXCL8B.3;CCL34B.9;Ccl21c;CXCL19;CXCL11.8
glucose transmembrane transporter activitySLC2A3;SLC2A15B;SLC2A8;SLC2A2;SLC2A3A;PPBP;SLC2A11B;SLC2A6;SLC2A5
growth factor activityGH1;EPGN;NRG1;TIMP1;LFT2;NENF;PDGFD;JAG2;ANGPTL3

PPBP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPBP here. Most of them are supplied by our site. Hope this information will be useful for your research of PPBP.

EFNA1; NR4A1; RPS27; DMWD; PMAIP1; COX17; MAPK6; MOB3B; rarD; SCFD1; fadE; CELF1; QRSL1; STRN4; PLEKHJ1; NDUFB11; CMTM6; COPS7A; COPG1

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