Active Recombinant Human PPBP Protein (70 aa)
Cat.No. : | PPBP-215P |
Product Overview : | Recombinant human NAP-2/CXCL7 produced in CHO cells is a single polypeptide chain containing 70 amino acids. A fully biologically active molecule, rhNAP-2/CXCL7 has a molecular mass of 9 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques. |
- Specification
- Gene Information
- Related Products
Description : | Chemokine (C-X-C motif) ligand(CXCL7) is a small cytokine belonging to the CXC chemokine family. It is an isoform of Beta-Thromboglobulin or Pro-Platelet basic protein (PPBP). CXCL7can signal through the CXCR1 and CXCR2 receptors. It is a protein that is released in large amounts from platelets following their activation. It stimulates various processes including mitogenesis, synthesis of extracellular matrix, glucose metabolism and synthesis of plasminogen activator. |
Source : | CHO |
Species : | Human |
Form : | Sterile Filtered White lyophilized (freeze-dried) powder. |
Bio-activity : | The EC50 value of human NAP-2/CXCL7 on Ca^2+ mobilization assay in CHO-K1/Ga15/hCXCR1 cells (human Ga15 and human CXCR1 stably expressed in CHO-K1 cells) is less than 0.1 μg/mL. |
Molecular Mass : | 9 kDa, observed by reducing SDS-PAGE. |
Protein Length : | 70 |
AA Sequence : | AELRCMCIKTTSGIHPKNIQSLEVI GKGTHCNQVEVIATLKDGRKICLDP DAPRIKKIVQKKLAGDESAD |
Endotoxin : | < 0.2 EU/μg, determined by LAL method. |
Purity : | > 98% as analyzed by SDS-PAGE. |
Storage : | Lyophilized recombinant humanNAP-2/CXCL7 remains stable up to 6 months at -80 centigrade from date of receipt. Upon reconstitution, human NAP-2/CXCL7 should be stable up to 1 week at 4 centigrade or up to 2 months at -20 centigrade. |
Storage Buffer : | Lyophilized after extensive dialysis against PBS. |
Reconstitution : | Reconstituted in ddH2O or PBS at 100 μg/mL. |
Gene Name : | PPBP pro-platelet basic protein [ Homo sapiens (human) ] |
Official Symbol : | PPBP |
Synonyms : | PPBP; pro-platelet basic protein; PBP; TC1; TC2; TGB; LDGF; MDGF; TGB1; B-TG1; CTAP3; CXCL7; NAP-2; SCYB7; THBGB; LA-PF4; THBGB1; Beta-TG; CTAPIII; CTAP-III; platelet basic protein; C-X-C motif chemokine 7; CXC chemokine ligand 7; beta-thromboglobulin; chemokine (C-X-C motif) ligand 7; connective tissue-activating peptide III; leukocyte-derived growth factor; low-affinity platelet factor IV; macrophage-derived growth factor; neutrophil-activating peptide 2; small inducible cytokine B7; small inducible cytokine subfamily B, member 7; thrombocidin 1; thrombocidin 2; thromboglobulin, beta-1; |
Gene ID : | 5473 |
mRNA Refseq : | NM_002704 |
Protein Refseq : | NP_002695 |
MIM : | 121010 |
UniProt ID : | P02775 |
Products Types
◆ Native Protein | ||
PPBP-30279TH | Native Human PPBP | +Inquiry |
◆ Lysates | ||
PPBP-1616RCL | Recombinant Rat PPBP cell lysate | +Inquiry |
PPBP-1397CCL | Recombinant Cynomolgus PPBP cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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