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TXNRD1

  • Official Full Name

    thioredoxin reductase 1

  • Overview

    TRXR1 (thioredoxin reductase 1) is a selenocysteine-containing protein that is involved in redox homeostasis. Its canonical target is thioredoxin, another redox protein. Together, they are involved in many functions such as antioxidant regulation, cell pr
  • Synonyms

    TXNRD1; thioredoxin reductase 1; thioredoxin reductase 1, cytoplasmic; GRIM 12; Trxr1; TXNR; oxidoreductase; thioredoxin reductase TR1; thioredoxin reductase GRIM-12; KM-102-derived reductase-like factor; gene associated with retinoic and IFN-induced mort;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • C. elegans
  • Chicken
  • Human
  • Mouse
  • Rat
  • Thauera selenatis
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
  • Tag Free
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TXNRD1-1117H Active Recombinant Human Thioredoxin Reductase 1 E.coli N/A
Human TXNRD1-2497H Recombinant Human Thioredoxin Reductase 1, His-tagged E.coli His
Human TXNRD1-3506H Recombinant Human TXNRD1, GST-tagged E.coli GST C-term-300aa
Human TXNRD1-1866HCL Recombinant Human TXNRD1 cell lysate N/A
Human TXNRD1-5936H Recombinant Human TXNRD1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human TXNRD1-2969H Recombinant Human TXNRD1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human TXNRD1-32H Recombinant Human Thioredoxin reductase 1 Protein, His-tagged HEK293 His
Human TXNRD1-4377H Recombinant Human TXNRD1 protein, His-tagged E.coli His 1-497aa
Human TXNRD1-6525H Recombinant Human TXNRD1 Protein (Lys150-Cys647), C-His tagged E.coli C-His Lys150-Cys647
Human TXNRD1-227H Recombinant Human TXNRD1 Protein, His-tagged E.coli His Tyr 161-Cys 647
Human TXNRD1-22H Recombinant Human TXNRD1 Protein Tag Free
Human TXNRD1-517H Recombinant Human TXNRD1 Protein, His-tagged E.coli N-His Gly412-Cys646
Human TXNRD1-6526H Recombinant Human TXNRD1 Protein (Met1-Cys647), C-His tagged Mammalian cells C-His Met1-Cys647
Mouse Txnrd1-736M Recombinant Mouse Thioredoxin Reductase 1, His-tagged E.coli His
Mouse Txnrd1-684M Recombinant Mouse Txnrd1 protein, His & T7-tagged E.coli His/T7 Glu374~Gln577 (Accession # Q9JMH6)
Mouse TXNRD1-17667M Recombinant Mouse TXNRD1 Protein Mammalian Cell His
Mouse TXNRD1-9793M-B Recombinant Mouse TXNRD1 Protein Pre-coupled Magnetic Beads HEK293
Mouse TXNRD1-9793M Recombinant Mouse TXNRD1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Txnrd1-6754M Recombinant Mouse Txnrd1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat Txnrd1-126R Active Recombinant Rat Thioredoxin Reductase 1 E.coli N/A
Rat TXNRD1-6378R Recombinant Rat TXNRD1 Protein Mammalian Cell His
Rat Txnrd1-685R Recombinant Rat Txnrd1 protein, His & T7-tagged E.coli His/T7 Phe208~Glu433 (Accession # O89049)
Rat TXNRD1-6034R Recombinant Rat TXNRD1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Txnrd1-22R Recombinant Rat Txnrd1 Protein Tag Free
Rat TXNRD1-6034R-B Recombinant Rat TXNRD1 Protein Pre-coupled Magnetic Beads HEK293
Rat Txnrd1-001R Recombinant Rat Txnrd1 Protein E. coli 3-499
Rat Txnrd1-021R Recombinant Rat Txnrd1 Protein E.coli
C. elegans TXNRD1-24C Recombinant C. elegans TXNRD1 Protein Tag Free
Thauera selenatis TXNRD1-109T Recombinant Thauera selenatis TXNRD1 Protein E.coli
Zebrafish TXNRD1-9695Z Recombinant Zebrafish TXNRD1 Mammalian Cell His
Chicken TXNRD1-2461C Recombinant Chicken TXNRD1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

TXNRD1 involved in several pathways and played different roles in them. We selected most pathways TXNRD1 participated on our site, such as Pyrimidine metabolism, Selenocompound metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with TXNRD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Pyrimidine metabolismNT5M;ITPA;RRM2B;NME1-NME2;CDA;PRIM2;DPYDA.1;NME3;PNP5A
Selenocompound metabolismMARS;TXNRD2;TXNRD1;CCBL1;PAPSS2A;SEPSECS;SEPHS1;MTR;PAPSS1

TXNRD1 has several biochemical functions, for example, electron carrier activity, flavin adenine dinucleotide binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TXNRD1 itself. We selected most functions TXNRD1 had, and list some proteins which have the same functions with TXNRD1. You can find most of the proteins on our site.

Function Related Protein
electron carrier activityHAAO;POR;ACOX3;ACOX2;DERL3;ME1;ETFB;MAOB;IVD
flavin adenine dinucleotide bindingGULO;DMGDH;GCDH;NOX5;AIFM4;NDOR1;MTHFR;DUS4L;TXNRD3
protein bindingLCP2;C1orf94;SAFB;MC2R;IL32;DDL-2;RG9MTD1;TRIM3;RYR2
protein disulfide oxidoreductase activityCCS;PTGESL;SH3BGRL3;TXNRD3;TXNL1;GLRX2;GLRX3;DNAJC10;TXN2
thioredoxin-disulfide reductase activityTRR1;TXNRD2;NXN;TXNRD1;TXNRD3

TXNRD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TXNRD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TXNRD1.

CAV1; Cav1; fhuB; DMRTC2; PPP1R16A

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