Recombinant Human TXNRD1 Protein, MYC/DDK-tagged

Cat.No. : TXNRD1-2969H
Product Overview : Recombinant Human TXNRD1 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.
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Description : This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 54.6 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : TXNRD1 thioredoxin reductase 1 [ Homo sapiens ]
Official Symbol : TXNRD1
Synonyms : GRIM-12; TR; TR1; TRXR1; TXNR
Gene ID : 7296
mRNA Refseq : NM_001093771
Protein Refseq : NP_001087240
MIM : 601112
UniProt ID : Q16881

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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