Recombinant Rat Txnrd1 Protein

Cat.No. : Txnrd1-22R
Product Overview : Recombinant Rat Thioredoxin Reductase 1 (Non-tagged, 499 residues)
  • Specification
  • Gene Information
  • Related Products
  • Download
Description : The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are found in mammals. TrxRs are selenocysteine-containing flavoenzymes, which reduce thioredoxins, as well as other substrates, and play a key role in redox homoeostasis. This gene encodes an ubiquitously expressed, cytosolic form of TrxR, which functions as a homodimer containing FAD, and selenocysteine (Sec) at the active site. Sec is encoded by UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing, primarily at the 5' end, results in transcript variants encoding same or different isoforms.
Species : Rat
Tag : Tag Free
Purity : ≥ 95% as judged by gel analysis
Unit Definition : 1 U of enzyme reduces 1 μmol DTNB per min in 0.5 mL standard DTNB assay containing 2.5 mM DTNB and 0.3 mM NADPH in TE buffer (50 mM Tris-HCl, 2 mM EDTA, pH 7.5)
Applications : DTNB assay; Insulin-coupled Thioredoxin assay; Inhibitor screening; etc.
Notes : Centrifuge the tube briefly before opening the lid
Storage : Store at -20 centigrade upon delivery.
Concentration : 1 mg/mL
Storage Buffer : TE buffer with 50% glycerol.
SDS-PAGE: Lane 1: Molecular weight marker<br />Lane 2: RTRXR1
Gene Name : Txnrd1 thioredoxin reductase 1 [ Rattus norvegicus (Norway rat) ]
Official Symbol : Txnrd1
Synonyms : TXNRD1; thioredoxin reductase 1; TR; TR1; TXNR; TRXR1; GRIM-12; thioredoxin reductase 1, cytoplasmic; KM-102-derived reductase-like factor; gene associated with retinoic and IFN-induced mortality 12 protein; gene associated with retinoic and interferon-induced mortality 12 protein; oxidoreductase; peroxidase TXNRD1; selenoprotein TXNRD1; testis tissue sperm-binding protein Li 46a; thioredoxin reductase GRIM-12; thioredoxin reductase TR1; EC; EC
Gene ID : 58819
mRNA Refseq : NM_031614
Protein Refseq : NP_113802
UniProt ID : O89049

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.


  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All Txnrd1 Products

Required fields are marked with *

My Review for All Txnrd1 Products

Required fields are marked with *


Inquiry Basket



Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /
  • Service lnquiry:

Stay Updated on the Latest Bioscience Trends