b2m

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b2m

Official Full Name beta-2-microglobulin
Background This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.
Synonyms B2M; beta-2-microglobulin; Beta-2-microglobulin; beta chain of MHC class I molecules; beta-2-microglobin
    • Species :
    • Bovine
    • Chicken
    • Cynomolgus
    • Cynomolgus Monkey
    • Cynomolgus/Rhesus macaque
    • Dog
    • Feline
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293F
    • HEK293T
    • Human Cell
    • Human Tissue
    • Human Urine
    • Human urine frompatients with tubular proteinuria
    • Insect Cell
    • Mammalian Cell
    • Wheat Germ
    • Yeast
    • Tag :
    • DDK
    • GST
    • His
    • Avi
    • StrepII
    • His-Avi
    • Myc/DDK
    • Myc
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human B2M-002H Recombinant Human B2M protein, GST-tagged Wheat Germ GST
    Human B2M-10092H Recombinant Human B2M, GST-tagged E.coli GST
    Human B2M-13H Native Human B2M Human Tissue N/A
    Human B2M-1656H Recombinant Human B2M protein, His-tagged HEK293 His
    Human B2M-1905H Recombinant Human Beta-2-Microglobulin Insect Cell His
    Human B2M-205H Recombinant Human B2M Protein, DDK-tagged Insect Cell DDK
    Human B2M-206H Recombinant Human B2M Protein HEK293 N/A
    Human B2M-218H Recombinant Human B2M, C13&N15-labeled HEK293 N/A
    Human B2M-2204HCL Recombinant Human B2M cell lysate Human Cell N/A
    Human B2M-2208H Recombinant Human B2M Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human B2M-26758TH Recombinant Human B2M, His-tagged E.coli His
    Human B2M-26790TH Recombinant Human B2M E.coli N/A
    Human B2M-2722H Recombinant Human Beta-2-microglobulin, His-tagged E.coli His
    Human B2M-315H Recombinant Human B2M Protein, His-tagged E.coli His
    Human B2M-3237H Recombinant Human B2M, His tagged Human Cell His
    Human B2M-443H Recombinant Human B2M protein, His-tagged HEK293F His
    Human B2M-5366H Native Human Beta-2-Microglobulin Human urine frompatients with tubular proteinuria N/A
    Human B2M-6236H Recombinant Human B2M Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human B2M-6H Human beta 2-Microglobulin Reference Standard N/A
    Human B2M-76H Recombinant Human B2M, His-tagged Yeast His
    Human B2M-8046H Native Human Beta 2 MicroGlobulin Human Urine N/A
    Human B2M-81H Recombinant Human Beta-2-microglobulin E.coli N/A
    Human CD1B & B2M-001HCL Recombinant Human CD1B & B2M cell lysate Human Cell N/A
    Human CD1B & B2M-249H Recombinant Human CD1B & B2M protein, His-tagged HEK293 His
    Human CD1D & B2M-001HCL Recombinant Human CD1D & B2M cell lysate Human Cell N/A
    Human CD1D & B2M-250H Recombinant Human CD1D(Met1-Ser301)& B2M(Met1-Met119) protein, His-tagged HEK293 His
    Human FCGRT & B2M Recombinant Human FCGRT & B2M Protein, His/Strep II-tagged, Biotinylated HEK293 His/StrepII
    Human FCGRT & B2M-1925HCL Recombinant Human FCGRT & B2M cell lysate Human Cell N/A
    Human FCGRT & B2M-1928H Recombinant Human FCGRT & B2M Protein, His-Avi/Strep II-tagged, Biotinylated HEK293 His/Avi/StrepII
    Mouse B2m & Fcgrt-054M Recombinant Mouse B2m & Fcgrt protein, His-Avi-tagged HEK293 His-Avi
    Mouse B2M-1656MCL Recombinant Mouse B2M cell lysate Human Cell N/A
    Mouse B2m-316M Recombinant Mouse B2m Protein, His-tagged E.coli His
    Mouse B2m-685M Recombinant Mouse B2m Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Mouse B2M-938M Recombinant Mouse B2M Protein, His-tagged HEK293 His
    Mouse FCGRT & B2M-1545MCL Recombinant Mouse FCGRT & B2M cell lysate Human Cell N/A
    Rat B2M-1111R Recombinant Rat B2M protein, His-tagged HEK293 His
    Rat B2M-1550RCL Recombinant Rat B2M cell lysate Human Cell N/A
    Rat B2m-317R Recombinant Rat B2m Protein, His-tagged E.coli His
    Rat B2m-72R Rat beta 2-Microglobulin Reference Standard N/A
    Rat B2M-913R Recombinant Rat B2M Protein Mammalian Cell His
    Rat FCGRT & B2M-1535RCL Recombinant Rat FCGRT & B2M cell lysate Human Cell N/A
    Cynomolgus Monkey B2M-1200C Recombinant Cynomolgus B2M Protein, His-tagged HEK293 His
    Cynomolgus Monkey B2M-1512CCL Recombinant Cynomolgus B2M cell lysate Human Cell N/A
    Cynomolgus Monkey CD1E & B2M-001CCL Recombinant Cynomolgus CD1E & B2M cell lysate Human Cell N/A
    Cynomolgus Monkey CD1E & B2M-197C Recombinant Cynomolgus CD1E & B2M protein, His-tagged HEK293 His
    Cynomolgus FCGRT & B2M-1533C Recombinant Cynomolgus FCGRT & B2M protein (Met 1-Met 119), His-tagged HEK293 His
    Cynomolgus Monkey FCGRT & B2M-1534CCL Recombinant Cynomolgus FCGRT & B2M cell lysate Human Cell N/A
    Dog B2M-314D Recombinant Dog TRIM21 Protein, His/GST-tagged E.coli His/GST
    Bovine FCGRT & B2M-11B Recombinant Bovine FCGRT & B2M Protein, His-Avi-tagged, Biotinylated HEK293 His/Avi
    Chicken B2M-1146C Recombinant Chicken B2M Mammalian Cell His
    Zebrafish B2M-7425Z Recombinant Zebrafish B2M Mammalian Cell His
    Cynomolgus/Rhesus macaque B2M-488R Recombinant Cynomolgus/Rhesus macaque B2M protein, His-tagged HEK293 His
    Feline FCGRT & B2M-12F Recombinant Feline FCGRT & B2M Protein, His-Avi-tagged, Biotinylated HEK293 His/Avi

    b2m involved in several pathways and played different roles in them. We selected most pathways b2m participated on our site, such as Antigen processing and presentation, which may be useful for your reference. Also, other proteins which involved in the same pathway with b2m were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Antigen processing and presentation HSPA6; CD8B; HLA-DRB1; HLA-C; HSPA1L; KLRC4; KIR2DS4; HSP90AB1; KIR2DS2; KIR3DL2

    b2m has several biochemical functions, for example, glycoprotein binding, identical protein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by b2m itself. We selected most functions b2m had, and list some proteins which have the same functions with b2m. You can find most of the proteins on our site.

    Function Related Protein
    glycoprotein binding Itgam&Itgb2; FBXO17; CALR; ERLEC1; B2M; TFRC; THBS1; LACRT; HSPA5; APOH
    identical protein binding NQO1; RGMB; PIP4K2C; DPP9; LDHB; DIAPH1; UBE4A; OAT; TLR3; TRIP10
    protein binding C10orf62; XK; PACSIN3; TOR1A; PCDH18; MYCBP2; MAPK4; EPHA7; GCC2; HSPA6

    b2m has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with b2m here. Most of them are supplied by our site. Hope this information will be useful for your research of b2m.

    HFE; CD1A; CD1B; HLA-A

    Oliveira, AC; de Sevilla, AF; et al. Prospective study of prognostic factors in asymptomatic patients with B-cell chronic lymphocytic leukemia-like lymphocytosis: the cut-off of 11 x 10(9)/L monoclonal lymphocytes better identifies subgroups with different outcomes. ANNALS OF HEMATOLOGY 94:627-632(2015).
    Park, SJ; Kwon, SG; et al. Selection of appropriate reference genes for RT-qPCR analysis in Berkshire, Duroc, Landrace, and Yorkshire pigs. GENE 558:152-158(2015).

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