|Official Full Name||beta-2-microglobulin|
|Background||This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.|
|Synonyms||B2M; beta-2-microglobulin; Beta-2-microglobulin; beta chain of MHC class I molecules; beta-2-microglobin|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
b2m involved in several pathways and played different roles in them. We selected most pathways b2m participated on our site, such as Antigen processing and presentation, which may be useful for your reference. Also, other proteins which involved in the same pathway with b2m were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Antigen processing and presentation||HSPA6; CD8B; HLA-DRB1; HLA-C; HSPA1L; KLRC4; KIR2DS4; HSP90AB1; KIR2DS2; KIR3DL2|
b2m has several biochemical functions, for example, glycoprotein binding, identical protein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by b2m itself. We selected most functions b2m had, and list some proteins which have the same functions with b2m. You can find most of the proteins on our site.
|glycoprotein binding||Itgam&Itgb2; FBXO17; CALR; ERLEC1; B2M; TFRC; THBS1; LACRT; HSPA5; APOH|
|identical protein binding||NQO1; RGMB; PIP4K2C; DPP9; LDHB; DIAPH1; UBE4A; OAT; TLR3; TRIP10|
|protein binding||C10orf62; XK; PACSIN3; TOR1A; PCDH18; MYCBP2; MAPK4; EPHA7; GCC2; HSPA6|
b2m has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with b2m here. Most of them are supplied by our site. Hope this information will be useful for your research of b2m.
HFE; CD1A; CD1B; HLA-A