BSG
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Official Full Name
basigin (Ok blood group)
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Background
The protein encoded by this gene is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. The encoded protein is also a member of the immunoglobulin superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] -
Synonyms
BSG; basigin (Ok blood group); M6; OK; 5F7; TCSF; CD147; EMMPRIN; basigin; CD147 antigen; OK blood group antigen; collagenase stimulatory factor; leukocyte activation antigen M6; extracellular matrix metalloproteinase inducer; tumor cell-derived collagenase stimulatory factor;
- Involved Pathway
- Protein Function
- Interacting Protein
- BSG Related Articles
BSG involved in several pathways and played different roles in them. We selected most pathways BSG participated on our site, such as Basigin interactions, Cell surface interactions at the vascular wall, Degradation of the extracellular matrix, which may be useful for your reference. Also, other proteins which involved in the same pathway with BSG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Basigin interactions | SLC3A2B;SLC7A11;SLC16A1;ITGB1B.1;BSG;SLC7A6;SLC3A2A;SLC7A8A;PPIA |
| Cell surface interactions at the vascular wall | BSG;SLC16A1;SIRPA;CEACAM6;DOK2;TREM1;AMICA1;GRB14;SLC7A11 |
| Degradation of the extracellular matrix | CTSL1;MMP15;BSG;MMP19;COL9A1;ADAMTS18;TLL1;COL25A1;BMP1B |
| Extracellular matrix organization | COL17A1A;ADAMTS18;KLK7;MMP17;TLL1;COL25A1;COL4A3;DDR2;ADAMTS4 |
| Hemostasis | AASS;IRF2;CBX5;MGC173646;PROCR;KIF5A;CD84;EHD1;AKAP1B |
| Integrin cell surface interactions | COL9A1B;FBN1;COL9A1A;BSG;ICAM4;COL13A1;LOC100514666;COMP;COL23A1 |
| Matrix Metalloproteinases | MMP12;MMP8;BSG;MMP17;MMP27;MMP28;TIMP4;MMP24;MMP20 |
| Metabolism | SLC52A3;GLTPD1;NDOR1;SLC4A1A;AFMID;NOSIP;PPM1K;THEM5;HSD17B11 |
BSG has several biochemical functions, for example, mannose binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BSG itself. We selected most functions BSG had, and list some proteins which have the same functions with BSG. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| mannose binding | DPM1;CD207;LMAN2L;MANBA;MBL1;CLN5;MAN2B1;CD209;CD209B |
| protein binding | FGFRL1B;RND3;APOOL;COG7;BCL2A1A;PIF1;GPR177;FAM81B;IL17RA |
BSG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BSG here. Most of them are supplied by our site. Hope this information will be useful for your research of BSG.
RFXANK; Cdk1; Tubb4b; USP50; Haus4; Haus7; RANBP3; ATXN10; UBE2A; mviM6; dapF; PDLIM7; b3xyc5_sollc; cona_canen; ATF2; P
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