Recombinant Human BSG Protein, C-His-tagged

Cat.No. : BSG-134H
Product Overview : Recombinant Human BSG Protein with C-His tag was expressed in E. coli.
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Description : Basigin (EMMPRIN, CD147) is a type I integral membrane receptor protein belonging to the immunoglobulin superfamily. Basigin is a glycosylated protein with four known isoforms, of which isoform 2 is the most abundantly expressed. Multiple functions have been ascribed to Basigin; foremost among these is stimulating the secretion of extracellular matrix metalloproteinases by adjacent fibroblasts, a function which has been implicated in promoting tumor progression. Research studies have shown that Basigin is overexpressed by many tumor cells, and its expression level may correlate with tumor malignancy. A recent study identified the BASIGIN gene as a regulatory target of Slug, suggesting a role for Basigin in the process of epithelial-mesenchymal transition. Basigin has also been identified as a marker for a subset of highly suppressive regulatory T cells, and as an obligate receptor for the malarial parasite Plasmodium falciparum on human erythrocytes.
Source : E. coli
Species : Human
Tag : C-His
Molecular Mass : ~20 kDa
AA Sequence : EPGTVFTTVEDLGSKILLTCSLNDS ATEVTGHRWLKGGVVLKEDALPGQK TEFKVDSDDQWGEYSCVFLPEPMGT ANIQLHGPPRVKAVKSSEHINEGET AMLVCKSESVPPVTDWAWYKITDSE DKALMNGSESRFFVSSSQGRSELHI ENLNMEADPGQYRCNGTSSKGSDQA IITLRVRSHLA
Purity : Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE).
Notes : For research use only, not for use in diagnostic procedure.
Storage : Store at 4 centigrade short term. Aliquot and store at -20 centigrade long term. Avoid freeze-thaw cycles.
Concentration : ≥0.5 mg/mL
Storage Buffer : PBS, 4M Urea, pH7.4
Gene Name : BSG basigin (Ok blood group) [ Homo sapiens (human) ]
Official Symbol : BSG
Synonyms : BSG; basigin (Ok blood group); basigin (OK blood group) , OK; basigin; CD147; EMMPRIN; CD147 antigen; OK blood group antigen; collagenase stimulatory factor; leukocyte activation antigen M6; extracellular matrix metalloproteinase inducer; tumor cell-derived collagenase stimulatory factor; M6; OK; 5F7; TCSF;
Gene ID : 682
mRNA Refseq : NM_001728
Protein Refseq : NP_001719
MIM : 109480
UniProt ID : P35613

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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